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Objective To investigate the subcortical ischemic vascular disease (SIVD) depressive symptoms and cerebral blood flow velocity (CBFV) changes between. Selected under SIVD diagnostic criteria 57 patients, respectively, to investigate vascular risk factors, including hypertension, diabetes, lipid abnormalities, symptoms of heart disease, smoking, alcohol consumption, family history of cerebrovascular disease, mental illness and their family history; measurement systolic blood pressure, diastolic blood pressure; whether the abnormal electrocardiogram (ECG); biochemical tests of blood glucose, serum cholesterol (CH), triglyceride (TG). Respectively using the Mini Mental State Examination Scale (MMSE), the Montreal Cognitive Assessment (MoCA), Hamilton Depression Scale (HAMD) Scale for assessment of the patient's cognitive and depressive symptoms. Application will SIVD patients with leukoaraiosis (LA) is divided into four the GE Signa1.5T superconducting magnetic resonance Abaron-Peretz standard. Application of the 2-MHz pulse wave TCD monitor (Model: GE Vivid 7 Dimension) measuring SIVD patients CBFV probing depth of 50 to 55 mm (MCA), 60 to 70 mm (ACA), 60 ~ 70mmP2 zone (PCA) . Probe 15 connected to the cardiac cycle in accordance with the middle cerebral artery (MCA), the anterior cerebral artery (ACA), the posterior cerebral artery (PCA) in the order, within 3 minutes of recording the lower sides MCA (MCA-R, MCA-L) both sides of the ACA (ACA-R, ACA-L) and PCA (PCA-R, PCA-L) on both sides of the contraction of the peak (Systolic CBFV, Vs), end-diastolic velocity (the the diastolic CBFV VD), average flow velocity (Mean CBFV, Vm), obtained average number as statistical data. Results 57 cases SIVD patients according to HAMD score 20 for The Standard: SIVD with depression group (SIVD-D, n = 27), and is not associated with the depression group (SIVD-ND, n = 30), was 47.4%. SIVD-D group and SIVD-ND group in gender, age, education level of no significant difference (P gt; 0.05). Vascular risk factors for the two groups of subjects had no significant differences in vascular risk factors of the two groups evenly distributed. Group of MMSE SIVD-D and MoCA score and SIVD-ND group there was no significant difference (P gt; 0.05). Group SIVD-D 2 14 3 13 cases; SIVD-ND the group, two of 16 cases, three of 14 cases; degree of two groups of subjects LA was no significant difference (P gt; 0.05). The SIVD-D groups on both sides of MCA and ACA CBFV than SIVD the-ND group were significantly lower (P lt; 0.05 to 0.001); SIVD-D group of the left MCA and ACA CBFV than the right side there were significant differences (P lt ; 0.05 to 0.001); SIVD-D groups on both sides of PCA CBFV SIVD-ND group showed no significant difference (P gt; 0.05). The patients with conclusions SIVD widespread symptoms of depression. SIVD associated with depressive symptoms CBFV reduce the presence of MCA and ACA, the left more than the right side to reduce significantly. The two sets of imaging results (MRI leukoaraiosis grading) showed no significant differences, suggesting CBFV change compared with the structural changes to more early to reflect the pathophysiological changes SIVD accompanied by symptoms of depression.
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