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Objective: This article by carotid ultrasonography in patients with cerebral infarction (cerebral infarction), to discuss the relationship between carotid atherosclerosis (carotid atherosclerosis, CAS) with cerebral infarction. And investigated according to blood pressure, blood sugar, blood lipids, atherosclerosis risk factors. Methods: Dalian Medical University Second Affiliated Hospital of Neurology in April 2008 - October 2009 patients with acute non-progressive cerebral infarction treated 256 cases, 50 cases of patients with progressive cerebral infarction, non-cerebrovascular diseases (such as Parkinson's disease, movement neuron disease, peripheral neuropathy, spinal cord lesions) of 100 patients, respectively, as a non-progressive cerebral infarction group, progressive cerebral infarction group and control group. After admission, routine monitoring of blood pressure, blood sugar, blood lipids (total cholesterol, TC, triglycerides TG, low-density lipoprotein cholesterol, LDL-C, high-density lipoprotein cholesterol HDL-C). Carotid ultrasound to measure blood vessel diameter and vessel wall intima - media thickness (IMT), presence or absence of atherosclerotic plaque formation and plaque echo intensity, location, shape, size, quantity, luminal stenosis and its extent. Results: 1. Progressive cerebral infarction group atherosclerotic plaque detection rate of 90% the soft spot detection rate of 74%; non-progressive cerebral infarction group atherosclerotic plaque detection rate of 78.9%, a soft spot check a rate of 58.6%: 45% of the control group atherosclerotic plaque detection rate, soft plaque detection rate of 9%, three significant difference (P lt; 0.05); mixing of the three spots, hard spots and IMT thickening of the detection rate was no significant difference (P gt; 0.05). Progressive cerebral infarction group artery stenosis in 48 patients (96%), severe arterial stenosis in 16 patients (32%); the non progressive cerebral infarction group artery stenosis in 216 cases (84.4%), severe stenosis 32 cases (12.5%); artery stenosis control group of 56 patients (56%), severe arterial stenosis in 4 cases (4%), three were statistically significant (P lt; 0.05). (3) the non-progressive cerebral infarction group the infarction side of the non-infarcted side plaques number of cases there was no significant difference (P GT; 0.05), the infarction side of the soft plaque was 58.8%, severe stenosis (38.8%), significantly higher than the non- infarction side (P lt; 0.01). Common risk factors of atherosclerosis, results in a = 0.05 level, age, male gender, hypertension, diabetes, LDL-c to its increased risk factors. Conclusions: 1. Carotid atherosclerosis is one of the important risk factor for ischemic cerebrovascular disease. Domestic and international studies agree that the occurrence of ischemic cerebrovascular disease not only the degree of stenosis of the lumen, and the nature and arterial plaque. This study shows that patients with cerebral infarction, carotid atherosclerosis, soft spots and severe arterial stenosis detection rate was significantly higher than non-patients with cerebral infarction, consistent with those reported. 2. Foreign research reports the atherosclerotic nature and degree of stenosis and progressive ischemic stroke are closely related. This study shows that progressive cerebral infarction carotid atherosclerotic plaque in artery stenosis and severe lower incidence of non-progressive cerebral infarction were significantly higher, especially in the higher incidence of soft plaque. In this study, 8% of patients with progressive cerebral infarction were not detected in atherosclerotic plaques, consider the cause of the progress of this part of stroke in patients with systemic factors, such as high blood sugar, fever, infection. 3 This study shows that patients with cerebral infarction infarction side with the non-infarcted side artery atherosclerosis and arterial stenosis detection rate showed no significant difference, but with the nature of the plaque, arterial stenosis, indicating the nature of the plaque and artery stenosis reflect cerebrovascular disease are at high risk. 4 This study once again confirmed that age, male gender, diabetes, high blood pressure, increased LDL-C is a risk factor for cerebral infarction, ischemic cerebrovascular disease is a complex of many factors. Many studies have shown that smoking is a risk factor for arterial atherosclerosis, this study did not reach this conclusion, consider some patients not smoking, but long-term exposure to environmental tobacco smoke also can cause atherosclerosis.
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