Dissertation > Excellent graduate degree dissertation topics show

The Influence on Plasma Levels of IL-1β and IL-6 in Patients with Different Pacing Sections of Right Ventricular Early

Author: ChenLiJuan
Tutor: LiXueWen
School: Shanxi Medical
Course: Internal Medicine
Keywords: right ventricular apex right ventricular septum ventricular electro-excitement Interleukin-1β Interleukin-6
CLC: R541.7
Type: Master's thesis
Year: 2010
Downloads: 15
Quote: 0
Read: Download Dissertation

Abstract


Objective:We sought to find the ideal pacing section by comparing the influence to patients’ plasma levels of Interleukin-1βand Interleukin-6 in right ventricular apex pacing early with that in right ventricular septum pacing early.Methods:We selected 60 patients with permanent cardiac pacemaker implantation, who implanted type DDD or DDDR pacemaker, and separated them into three groups according to different ventricular lead placement and different pacing ratio of right ventricular:right ventricular apex (RVA) pacing group, right ventricular septum (RVS) pacing group and the matched group. We compared their preoperative electrocardiogram with their own cardiac rhythm, and the time limit and shapes of QRS waves on their pacing electrocardiogram, as well to observe and compare the postoperative changes of plasma levels of Interleukin-1β(IL-1β) and levels of Interleukin-6 (IL-6) between three groups besides in a week and in three mouths.Results:(1)the time limit of QRS waves on their pacing electrocardiogram in right ventricular apex pacing group is greater obviously than that in right ventricular septum pacing group after implant pacemaker, and this difference between them has statistical significance (P<0.05);(2)①neither the preoperative plasma levels of IL-1βnor the preoperative plasma levels of IL-6 between three groups has statistical difference (P>0.05);②fter operation a week, plasma levels of IL-1βin both RVA pacing group and RVS pacing group go up by comparing with their preoperative levels respectively, and it is higher obviously in RVA pacing group than that in RVS pacing group (P<0.05);after operation three mouths, plasma levels of IL-1βin RVA pacing group is higher than preoperative quantity, which is statistically significant (P<0.05); the plasma levels of IL-1βcomparing with preoperative levels in RVS pacing group has no statistical difference (P>0.05), and plasma levels of IL-1βin RVA pacing group is significantly higher than that in RVS pacing group (P<0.05);③fter operation a week, plasma levels of IL-6 are significantly higher than preoperative’s both in RVA pacing group and in RVS pacing group, and it is similar when implanting pacemaker three mouths later (P<0.05); plasma levels of IL-6 in RVA pacing group is significantly higher than that in RVS pacing group both after operation a week and three mouths (P<0.05); ④The correlationship between plasma levels of IL-1βand IL-6 of three groups in above-mentioned periods have no significance (P>0.05), but the correlationship between IL-1βand IL-6 of three groups when analysis in the mass is positive correlation (P=0.000).Conclusion:the time limit of QRS waves with right ventricular septum pacing is less obviously than that with right ventricular apex pacing, right ventricular septum pacing is more advantageous in keeping the electro-excitement synchronism between both ventricles, and has more little influence to plasma levels of IL-1βand IL-6, which may reduce the disadvantageous influence to the heart function, so right ventricular septum is a relatively ideal pacing section.

Related Dissertations

  1. The Preliminary Study on Interleukin-10 Transgenic Mice,Q78
  2. Study on the Expression and Bioactivities of Porcine Interleukin-2/6 Fusion Protein in Vivo and in Vitro,S858.28
  3. The Influence in Different Route of Medication with Vitamin A on CD4~+CD25~+ Regulatory T Cell and Cell Factor of IL-4、 IFN-γ in a Rat Persistent Asthma Model,R562.25
  4. Observastion on Histomorphology, Ultrastructure and Expression of TNF-α, IL-1β of Unbalance of Dynamic and Static Forces Cervical Degeneration Disc in Rat Model Abstract,R681.55
  5. Improvement of Interleukin Profiles in Patients with Type 2 Diabetes Mellitus After Add-on Acarbose Therapy Independent of Glycemic Control,R587.1
  6. Effects on Recombinant Human Interleukin-10 of IL-2, IFN-γ, GCs, T Cell Apoptosis in Transplantation of the Rabbit Skin,R392
  7. Association of Interleukin-6 Gene Polymorphisms with Susceptibility to Coronary Heart Disease in Asian Populations: a Meta-analysis,R541.4
  8. Study on the Correlation Between the Levels of Il-18, IL-33 and Other Inflammatory Factors and Pulmonary Function in Different Stages of Asthma,R562.25
  9. Study on the Correlation btween Serum, Aqueous Humor VEGF, IL-6 Levels and the Neovascular Glaucoma,R775
  10. Restructuring Agkistrodon disintegrin Adinbitor human non-small cell lung cancer cell line A549,R285.5
  11. MPO, IL-18 and INF-γ expression in human coronary arteries with plaque stability and preliminary study,R541.4
  12. Bronchial asthma serum interleukin -16 Determination and clinical significance,R725.6
  13. IL-15 and IL-15 receptor α subunit of metastatic liver in Mice,R735.7
  14. p38MAPK on allergic rhinitis peripheral blood mononuclear cells IL-4, IL-5 effects,R765.21
  15. Aminophylline Treatment in Young Rabbits with Severe Meconium Aspiration Syndrome,S858.291
  16. The Role of Interleukin-1 and Interferon-γ in the Pathogenesis of Nasal Polyps,R765
  17. The Short-term Prognostic Significance of Depression for Patients with CHD Undergoing Revascularization,R541.4
  18. Punta grass Chubi decoction on serum inflammatory factors CIA Experimental Study on Effects,R285.5
  19. TCM sticking therapy on rabbit lumbar intervertebral disc IL-1α, IL-1β activity in rats,R274.9
  20. The Different Serum Levels of IL-2 and IL-6 and Its Significance in Patients with Allergic Rhinitis, Chronic Rhinosinusitis, and Nasal Poplys,R765.21
  21. Study on Related Factors and Serum Il-1β, IL-6 Levels in Patients with Progressive Cerebral Infarction,R743.3

CLC: > Medicine, health > Internal Medicine > Heart, blood vessels ( circulatory ) disease > Heart disease > Arrhythmia
© 2012 www.DissertationTopic.Net  Mobile