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ICU Bloodstream Infections and Antimicrobial Resistance of Pathogens

Author: LuoYunShan
Tutor: WanXianYao
School: Dalian Medical University
Course: Internal Medicine
Keywords: Septicemia Bacterial culture Antibiotic resistance ICU
CLC: R446.5
Type: Master's thesis
Year: 2010
Downloads: 65
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Abstract


Objective:To investigate the spectra and their drug resistance of pathogenjc bacteria in septicemia patients.Methods:The bacteria isolated from septicemia patients’blood were cultured and their antibiotic susceptibility was tested, Comparison of ranking the top 5 characteristics of bacterial resistance.Results:124 cases of bloodstream infection were detected in 149 patients with pathogenic bacteria, Gram-positive (G+) bacteria 83 accounting for 55.7%; Gram-negative (G-) bacteria 63, accounting for 42.3%; fungi 3, accounting for 2.0%. ICU infections in which bacteria 112, accounting for 75.2%; G+cocci 55 (accounting for 49.1%), G-bacilli 55 (accounting for 49.1%), fungi 2 (1.8%). The main pathogens causing bloodstream infection was followed by Burkholderia cepacia bacteria (33, 29.5%), Staphylococcus epidermidis (31,27.7%), Klebsiella pneumoniae (7,6.3%) and Staphyloccocus aureus Rosenbach (7,6.3%), human aureus (6,5.4%) and Acinetobacter baumannii (6,5.4%), Pseudomonas aeruginosa (5,4.5%) and Staphylococcus haemolyticus(5,4.5%), suggesting that G-bacteria with Burkholderia cepacia bacteria dominated, G+bacteria to coagulase-negative staphylococci in Staphylococcus epidermidis based. G+ cocci to vancomycin resistance rate was 0.0%.Conclusions:The past five years, our department in patients with septicemia pathogenic bacteria to G+bacteria and G-bacteria are basically the same. In G+the bacteria to coagulase-negative staphylococci in the mainly Staphylococcus epidermidis; in G-bacteria isolated from Burkholderia cepacia bacteria in to the main. In the G-bacilli in young carbon enzymes most sensitive enzyme-ene; and G+cocci to glycopeptide and oxazolidinone most sensitive to drug-resistant strains was not found.

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