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Studys on the Effect of Hypolipidemic of Nelumbo Nucifera Leaves Extracts

Author: GuoShuGuang
Tutor: XuQiTai；KangWenYi
School: Henan University
Course: Pharmacology
Keywords: Lotus leaf Madder Hyperlipidemia Fat emulsion Carbon tetrachloride Hepatoprotective Acute liver injury Liver fibrosis Antioxidant Mice
CLC: R285
Type: Master's thesis
Year: 2010
Downloads: 218
Quote: 0
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Abstract


This thesis is divided into four chapters . The first chapter discusses the use of the fat emulsion modeling hyperlipidemia in mice to evaluate the lotus leaf extract lipid-lowering activity . The second chapter discusses the use of carbon tetrachloride model of acute liver injury in mice to evaluate the lotus leaf , madder extract hepatoprotective effect . The third chapter discusses the use of carbon tetrachloride model of hepatic fibrosis in mice to evaluate the lotus leaf , madder extract hepatic fibrosis . The fourth chapter outlines the leaves of the chemical composition and pharmacological studies . The first chapter of lotus leaf extract lipid-lowering activity of this chapter discusses the preparation of vegetable oil, animal oil fat emulsion to establish a mouse model of hyperlipidemia , it was found that animal oil modeling results are better than vegetable oil . Study the leaves of the lipid-lowering activity The results NNEA the and NNBU have the role of a significant reduction in serum lipids in mice . The hepatoprotective effect the second chapter of the lotus leaf and madder extract research This chapter lotus leaf and madder extract protective role , the results showed significant hepatoprotective effect the lotus leaf NNEA and NNBU extract . Madder the RCPE, RCEA and MC extract showed a significant hepatoprotective effect . Chapter lotus leaf , madder extract hepatic fibrosis research This chapter examines the lotus leaf extract on liver fibrosis therapeutic effect in mice , the results show lotus leaf NNEA and the NNBU extract significant hepatic fibrosis . Madder the RCPE, RCEA and RMC extract showed a significant hepatic fibrosis . Research Overview This chapter of the fourth chapter of the lotus leaf chemical constituents and pharmacological activities of lotus leaf chemical composition and pharmacological research are reviewed.

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CLC: > Medicine, health > Chinese Medicine > Of Pharmacy > Pharmacology
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