|
Acupuncture treatment is not simply a direct effect on the pathogenic factors or lesions, their treatment is to rebuild the stability of immune system, so that the disease tends to rehabilitation, but the role of acupuncture for immune regulation and thus affect on nerves, endocrine system, the mechanism is through what channels, layers, affecting the body link is not yet clear, so in recent years, regulation of acupuncture on the immune mechanism research has become a hot topic, and to clarify its in-depth study of its acupuncture control mechanism is necessary.In this study, based on the previous experiment, trying to observeing acupuncture on adjuvant arthritis (AA) model rats and the use the theory of electrical properties of acupuncture combined with neuroendocrine-immune network, to reveal the overall control of the mechanism of acupuncture.Experiment with adjuvant arthritis model for this study, the current points test in rats, plasma and calcium content of cortical, spinal cord content of SP material to observe acupuncture-induced inflammation model of immune disorders.40 Wistar rats were selected randomly divided into 8 groups,5 rats in each group were:normal group, AA model group, AA needle Baihui group, AA Baihui moxibustion group, AA needle Guanyuan group, AA moxibustion Guanyuan group, AA needle Zusanli, AA moxibustion Zusanli group.Experiment concluded that the role of acupuncture adjustment is multifaceted, multi-link, multi-channel, multi-level, the result reflects the traditional Chinese medicine theory Baihui, Guanyuan, Zusanli three points differ from the role of the characteristics and functions, through the characteristics of current flow through the acupuncture points, we understand the stress and inflammation in the pathological process and acupuncture on the body within the profile, fully embodied the argument "to the table to know where" and features of the traditional Chinese medicine.1. Current surface of acupuncture point was moderate under normal circumstances, indicating no real-time surface currents to stimulate the body and also showed the dynamic changes of rise and fall with the organs have a certain relevance.2. After the body received bad stress (adjuvant arthritis) for body organs with varying degrees of injury, the damage can be measured by the current value of that point, the performance of current through the acupuncture points reflect the body’s organs function, therefore reflects the point of "to the table to know where", but also suggests the current value of points within the body can reflect the pathological state and pathological processes.3. Found that when the body is inflammation, acupuncture three main points the current change can affect the existence of acupuncture points and the specificity of inflammation, the body plays a regulatory role of different state and change the current point has obvious relevance.4 Research found that acupuncture and moxibustion Baihui failed to inhibit the secondary immune reaction, but that through the current difference, Baihui acupuncture was significantly lower than the current margin Baihui moxibustion, According to other relevant results of this study shows acupuncture can relieve Baihui inflammation caused by psychological disorders; acupuncture Guanyuan and Zusanli can inhibit the secondary immune reaction, and moxibustion Guanyuan and Zusanli are not significantly inhibited the incidence, suggesting there is a difference between acupuncture and moxibustion treatment for inflammatory immune dysfunction caused by state regulation.5 Research shows that Baihui failed to restrain the secondary reaction, but the point reflect the current state of mind performance of the body; Guanyuan can inhibit the secondary reaction, and may reflect a function of body organs rise and fall of the situation; Zusanli normal state current fluctuations similar to the bilateral points, confirmed the theory of symmetry about the meridian, in the pathological process Zusanli difference left side of the current show greater than the right side "Canon" said "Strong in the right Weak disease in the left, or Strong in the Left Weak disease in the right" theory and perspectives, while the current values in the left is greater than the right side were also confirmed by the "ill treatment of left right, left-right-disease rule" theory, and can significantly inhibition of secondary reactions, consistent with the role of acupuncture in recent rules.6. Studies showed that Ca2+levels in plasma and cortex in the AA model, the performance of their different body caused by stress is closely related to the experimental results show that the self-acupuncture on immune cells or regulatory effect of nerve impulses, also reflected by regulating Ca2+Acupuncture anti-inflammatory analgesic play the role.7 Research shows that the level of the spinal cord SP reflected in the AA model of the body acupuncture can regulate the level of SP material, and inflammation occur in the immune cells play a regulatory role in the process of recruitment, and immune regulatory function in some specific cell functions are also affected.Integrated the above, the main three acupuncture point is adjustable to immune function, and the maximum mobilization of the upright human body can improve the stimulating stress resistance caused by outside the body, inhibition of noxious stimuli on the body side effects, and on the AA rats significantly inhibited inflammatory response and secondary immune response, which has a specific point. The results also shows that Ca2 levels by regulating acupuncture, spinal cord, reduced production and release of SP play an anti-inflammatory, anti-stress reaction. For two-way nature of acupuncture on the body depends on the overall regulation of nerve-endocrine-immune network and for the common control are all part of a regulatory role. Combination of acupuncture on the level of the relevant factors affecting speculated that acupuncture through multiple targets, multiple links to achieve the source of the stress caused by the regulation of immune dysfunctionAcupuncture regulation for the whole body most of the way through the neuro-endocrine-immune network, while the point is to play its role in the specificity of the foundation, the different ways the role of acupuncture points and its effect on the body are not the same. These results reflect the traditional Chinese medicine theory Baihui, Guan Yuan, Zusanli the role of three-point characteristics and laws of the different characteristics of current through the acupuncture points, understand stress and inflammation and the pathological process of acupuncture on the body in the internal profile, fully embodied the argument and features of the traditional Chinese medicine "to the table to know where". However, experiments only from inflammation and stress, pain and so initially revealed the role of the different characteristics and rules of acupuncture points, but not enough to reveal the overall level of the three acupuncture points, acupuncture points for the current and anti-inflammatory analgesic substance relevance and substance between calcium and P anti-inflammatory analgesia in correlation with each other, this is the next step of our features.
|