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The Study on the Effect of Serum IL-6 and Clinical Observation in Henoch-Schonlein Purpura Patients Treated Ba Xiaodian Soup

Author: YangWeiMin
Tutor: SunFeng
School: Heilongjiang University of Traditional Chinese Medicine
Course: Chinese medical science
Keywords: Purpura Consumer leucoderma soup IL-6
CLC: R259
Type: Master's thesis
Year: 2008
Downloads: 26
Quote: 0
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Abstract


Objective: In this study , patients with allergic purpura (HSP) as the research object , by observing the eliminate erythema soup therapy HSP clinical efficacy , as well as the change of serum IL-6 levels before and after the treatment of patients with HSP explore HSP pathogenesis and treatment of consumer leucoderma soup the HSP mechanism of action , clinical further applications eliminate erythema soup provide a theoretical basis for treatment of HSP . Methods: 52 cases of patients with HSP random number table is divided into a treatment group and a control group , n = 26 cases . Patients in both groups other drug treatment of HSP is disabled for more than one week . May cause sensitization by the Food and Drug Zhu Huanzhe avoid . The treatment group received eliminate erythema soup, the control group was given prednisone . Both groups a month for a course, determine the clinical efficacy of the two courses . Detected using ELISA in serum IL-6 levels before and after the treatment of patients with HSP . Results: 1. Elimination leucoderma soup efficacy exact total effective rate of 92.00% , prednisone total effective rate was 88.00% , the two groups showed no significant difference ( P > 0.05 ) . 2 treatment groups to improve the clinical symptoms and shorten the urine occult blood and urine protein time , superior to prednisone control group ( P <0.05 ) . Before treatment, patients with HSP of serum IL -6 level is higher than the normal group ; after treatment in both groups can make HSP serum IL-6 levels have decreased significantly , but still higher than the normal group . Conclusion: The clinical observation and tests that eliminate erythema soup is an effective prescription to treat HSP in improving clinical symptoms and shorten the urine occult blood and the time urinary protein is superior to prednisone treatment . HSP serum IL-6 levels , the levels were significantly decreased after treatment by the elimination leucoderma soup , the prompt elimination leucoderma soup may play a therapeutic effect by correcting HSP patients with immune dysfunction state .

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