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Comparison Results of Diagnosing Breast Carcinoma with Ultrasonography, Mammography and Combination of Both Modalities

Author: LengXiaoLing
Tutor: MaFuCheng
School: Xinjiang Medical University
Course: Medical Imaging and Nuclear Medicine
Keywords: Breast neoplasms Mammography Ultrasonography Doppler Color
CLC: R737.9
Type: Master's thesis
Year: 2008
Downloads: 156
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Abstract

Objective: To assess the value of ultrasonography combined with mammography in diagnosing breast cancer. Methods: 136 cases of breast cancer confirmed histologically had mammography and ultrasonography for diagnosis and differential diagnosis. To make combination diagnosis according to clinical findings, sonography, mammography, and combination of both modalities and the statistic analysis of data. Results: Considering of the age, ultrasonography was more sensitive than mammography in diagnosing malignant breast lesions for patients under the age of 50, and the sensitivity difference of X-ray mammography and ultrasound imaging was not statistically significant. Sensitivity of diagnosing breast cancer with ultrasonography was 87.5%, and sensitivity of diagnosing breast cancer with mammography was 73.5%. Sensitivity of ultrasonography and mammography together was 92.6%,which was different significantly (P<0.05)from the sensitivity obtained by ultrasonography or mammography alone. Conclusion: Complementation of ultrasonography and mammography can promote the diagnostic rate of breast cancer. The sensitivity of mammography depends on the tumor size which can be touched and the texture of breast, and the sensitivity of ultrasonography is related to tumor size, but not be affected by the gland texture. The importance of mammography should be emphasized on in the detection of breast cancer which can not be touched. Ultrasonography, mammography and bloody nipple discharge testing should be joint in complementary diagnosis. The main advantages of mammography are that the sensitivity of breast cancer over the age of 50 particularly ductal carcinoma in situ is higher than that of. ultrasonography. Obvious advantages of ultrasound are diagnosis on lesions which X-ray mammography can not be detected and qualitative benign and malignant under the age of 50 and make more accurate diagnostic classification. The sensitivity of invasive ductal carcinoma with ultrasonography is superior to that of mammography. The sensitivity of them to the invasive lobular carcinoma has no difference and is lower than other types of cancer. The sensitivity of mammography related to carcinoma in situ is superior to that of ultrasonography. Microcalcifications detection of ductal carcinoma in situ is the key, even the dense breast. Mammography is also useful detection of microcalcifications of carcinoma in situ. To the leisons that mammography only show minimal calcification, ultrasound imaging can inspect breast nodules (with or without calcification) and improve the diagnosis of confidence. To 0 Phase breast cancer, mammography sensitivity is more than ultrasonography. To Phase I of breast cancer, ultrasonography sensitivity is more than mammography. To the detection of breast cancer at Phase II and more than Phase II there is no statistical significance between ultrasound and mammography, but the ultrasonography detection rate on the suspicious axillary lymph nodes is significantly higher than that of mammography. Breast ultrasonography imaging and X-ray mammography can be combined to improve the sensitivity of breast cancer diagnosis, and more untouched breast cancer, occult breast cancer, dense breast cancer within the gland and in situ cancer can be detected.

Comparison Results of Diagnosing Breast Carcinoma with Ultrasonography, Mammography and Combination of Both Modalities

Abstract

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