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Objective: ventilator-associated pneumonia (ventilator associated pneumonia, VAP) , ICU (intensive care unit, ICU) is the most common nosocomial infections , VAP extended retain the time of the patients in the ICU , and increased health care costs . Investigate the the VAP clinical phase risk factors to provide a scientific basis for the prevention and treatment VAP . Methods: From January 2007 to August 2007 Check my hospital intensive care unit (ICU) clinical data of patients with greater than 48 hours of mechanical ventilation , the incidence of VAP group , diagnostic criteria and did not occur VAP group , the two groups of patients related risk factors for comparative analysis. Software statistical package (PEMS3.1) first single factor analysis may lead to the occurrence of VAP clinically relevant risk factors , including age , coma , days of mechanical ventilation , shock , heart failure , chronic obstructive pulmonary disease ( COPD ) , acute renal failure diabetes , antibiotics , hormones , the application of , and then backward method of multiple stepwise logistic regression analysis to determine independent risk factors for VAP . Results : VAP incidence of 46.1% , and the mortality rate was 11.5% . Univariate analysis results show that aspiration , coma , duration of mechanical ventilation and other nine factors are statistically significant . Multivariate Logistic regression analysis showed that the risk factors for incidence close 3 : aspiration , duration of mechanical ventilation and antibiotics in combination (≥ 2 ) . Conclusion: VAP have higher incidence and mortality , VAP with a variety of clinical factors are closely related. For the integrated management of VAP risk factors , focusing on surveillance , take a combination of different prevention strategies to prevent and reduce the incidence of VAP .
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