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The astragalus ground study of some chemical components

Author: LiuLi
Tutor: XuDongMing
School: Changchun University of Traditional Chinese Medicine
Course: Of Pharmacy
Keywords: Astragalus aerial parts The Astragaloside the Determination Saponins and flavonoids Structural identification
CLC: R284.1
Type: Master's thesis
Year: 2008
Downloads: 327
Quote: 1
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Abstract


Chinese Pharmacopoeia ( 2005 ) provides Astragalus (Radix Astragali) Bge.var.mongholicus ( Bge. ) Hsiao , of leguminous plants Mongolia the astragalus Astragalusmembranaceus ( Fisch. ) or Astragalus membranaceus Astragalusmembranaceus (Fisch) Bge dried root . Astragalus is blindly commonly used in traditional Chinese medicine, qi solid form , diuretic care drugs, abscess , sore myogenic effect . Clinically used for the Qi fatigue , eat less , loose stools , and subsidence in the air , chronic diarrhea , rectal prolapse , blood in the stool , bleeding, imaginary spontaneous table , Qi edema , ulcer difficult collapse , long collapse not grabbing , blood deficiency atrophy yellow , heat diabetes , chronic nephritis, proteinuria , and diabetes . The research papers on the Summary at home and abroad of Astragalus chemical composition and pharmacological research progress on the basis of this study , total astragalus saponins and astragaloside content in the Determination of Astragalus stems in , Astragalus stem , colorimetry and high performance liquid chromatography the total saponin content in the leaves as the 22.96mg / g Astragaloside 3.615mg / g, the method is simple , separated completely , good reproducibility and high precision, the results can be used to expand the herbal selection basis . Through the use of various means of chromatography , vacuum column chromatography on silica gel, macroporous resins, reverse Silicone four compounds were isolated from the aerial part of traditional Chinese medicine Astragalus , three compounds were identified by physicochemical properties and spectral resolution structure are : 5,7 - dihydroxy flavonoids , 5,7,4 ' the - trihydroxyflavone and astragalus A glycosides ( astragaloside IV ) , the in Astragalus roots of effective chemical composition of literature , to find the same ingredients . The experimental results show that Astragalus aerial parts and medicine Astragalus root has the same chemical composition , while the content is also high , and provide a reliable basis for the future expansion of the choice of herbal .

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CLC: > Medicine, health > Chinese Medicine > Of Pharmacy > Traditional Chinese medicine chemical > Chemical analysis and identification
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