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Objective: by observing the red glycosides pulse through the clinical efficacy of the injection in the treatment of stroke (blood stasis card), to evaluate drug safety, and to lay the foundation for clinical application. Methods: 1, clinical data in all cases is August 2007 - July Changchun University of Chinese Medicine Affiliated Hospital outpatient and hospitalized patients, a total of 72 cases were randomly divided into a control group and the experimental group, the experimental group and the control group 1:1 allocation. A basic balanced distribution of the two groups in age, gender, disease duration, and infarct location, there was no significant difference (p> 0.05), comparable. 2, drug usage test group: 2 red glycosides pulse each time through injection and a erigeron injection simulation agent added to 250ml of saline, slow intravenous infusion, day 1. Course of 14 days. Control group: each time through the of a erigeron injection and 2 red glycosides pulse injection simulation agent is added to 250 ml of normal saline, slow intravenous infusion, day 1. Course of 14 days. During the trial in both groups to stop using any other drugs that affect the efficacy of the drug evaluation. Security observation. Were before treatment, medication one week, general physical examination items check medication for two weeks: including body temperature, breathing, heart rate, blood pressure; respectively, before treatment, after treatment to check blood, urine, stools (including occult blood) routine laboratory tests and ECG liver function (ALT, AST), renal function (BUN, CRE) check; and do a head CT before treatment. The statistical methods count data with X ~ 2 test, measurement data using t test, the level of information Ridit test. Results: 1, TCM symptoms therapeutic evaluation: After treatment, the number of basic recovery for the three cases, the markedly effective in 12 cases, the effective number of 16 cases, the total effective rate was 86.11%, the control group after treatment, the number of basic recovery of the two cases, effective the number of 11 cases, the effective number of 17 cases, the total effective rate was 83.33%, Ridit analysis, no significant difference (P> 0.05) by statistical analysis, description the deficit glycosides Maitong injection of Chinese medicine clinical symptoms and signs have significant effects . 2, nerve function impairment degree efficacy determination: After treatment, the treatment group basic heal the number for the three cases, a significant 12 cases of progress in the number, 17 cases of progress in the number, total have efficiency of 88.89%, after treatment, the control group basically healed the number for the two cases, significant progress total 11 cases, progress in the number of 18 cases, the total effective rate was 86.11%, Ridit analysis, the two groups showed no significant difference (P> 0.05) to the deficit glycosides Maitong injection clinical neurological deficit improved significantly efficacy . The security detection: the treatment group and the test group during the clinical trials were not obvious adverse reactions and side effects. Two groups of laboratory tests (blood, urine, stool routine, liver and kidney function, blood clotting conventional) were not there before and after treatment with treatment-related abnormal changes, non-toxic, show that the drug side effects, effective and reliable, and safe to use. Conclusion: The treatment group and control group the clinical neurological defect degree of efficacy, TCM Syndrome integral by statistical analysis showed no significant difference (P> 0.05), detected by security at the same time, non-toxic side effects show that the drug is safe and reliable; above Chek glycosides veins through injection meridians (cerebral infarction) stasis stasis syndrome were TCM syndrome symptoms have a significant effect in the treatment of stroke patients, significant improvement of clinical degree of neurological deficits, and the use of safety.
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