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Prescription Effect judgment method binding compound compatibility between

Author: WuMengXu
Tutor: JiangYongGuang;ZhouXunLun
School: Chengdu University of Traditional Chinese Medicine
Course: Traditional Medical Formulae
Keywords: Prescription Traditional Chinese medicine Effect The data processing Knowledge Discovery
CLC: R289
Type: Master's thesis
Year: 2007
Downloads: 83
Quote: 0
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Abstract


Background: Prescription Effect prescription theoretical research and clinical applications have a crucial role. Prescription efficacy studies, however, there are some problems: the Cuban side efficacy Description; expressed lack of standardized part of the Prescription Effect; same efficacy, there are a variety of forms of representation; describe the same prescriptions have different effects; Prescription Effect has been summarized by the human, the lack of objective Analyzing methods. Objective: to the understanding of the basis of the theory of traditional Chinese medicine the other agent efficacy, drug data specification quantization process is based on database knowledge discovery techniques to explore by the prescription drug efficacy and its associated objective method to determine the effectiveness of all- Prescription Effect objective and quantitative method of determining the foundation. Methods: are summarized Prescription Effect of prescription drugs to determine the composition of the object and analyze the compatibility relations. Specifically, it involves two aspects: First, the prescription drug; Second, the composition of the relationship between drug prescription reflected the impact of the drug's efficacy in. These two aspects of the knowledge discovery in databases is essentially similar property Statute, embodied in: the one hand, the properties of the Statute and effectiveness inductive method to capture information based on objective data; other hand, it is not all objective data as no difference, they all get the main elements in the information provided, highlighting the essential attributes. The concrete steps of the method: the space vector method is based on the efficacy of the drug information to determine Prescription Effect; using a new technology on the international SimRank method to determine the degree of synergy between the drug's efficacy; drug and efficacy between the two-dimensional association rules mining association rules; establishment of drug efficacy based on data obtained by the first three multi-dimensional analytical model to carry out the research method to judge by the drug to the side effects. Results: The assessment of research results by comparing the \The results of the analysis of the basic party libraries prescription textbook describes efficacy consistent rate of 82.65%; than the space vector approximately 70% of the method and neural network method has a higher rate of matching efficiency is not high. Implications for research: (1) an objective judgment Prescription Effect, to avoid subjective factors, is conducive to objective and quantitative show the basic features of the prescription. (2) The results can be recorded on efficacy supplement in the Cuban side, the Cuban side to provide more references for clinical applications. (3) standardization of terms by the other agent efficacy, which is conducive to accurate knowledge of the effective prescription of clinicians and researchers, but also conducive to the combination of modern information technology to research and widely disseminated, add new ideas to the Chinese medicine research Methods.

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