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The Studies on Histopathology and Comparative Pathology of Liver Lipoma in Bactrian Camel

Author: ZhouDaPeng
Tutor: JiaNing
School: Gansu Agricultural University
Course: Basic Veterinary Science
Keywords: Bactrian camel Lipoma of the liver Epidemiology Histopathology Comparative Pathology
CLC: S858.24
Type: Master's thesis
Year: 2010
Downloads: 23
Quote: 0
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Abstract


In this study, the methods and means of the epidemiology, pathology, ultrastructure from Golmud, Qinghai, Inner Mongolia Cosby, Gansu Minqin County, a total of 236 cases of Bactrian camel liver lipoma were studied in detail, and with people fat The tumor depth comparison, the results showed that: Bactrian camel liver with a high incidence of lipoma, pop wide range, have a serious impact on the the Bactrian camel liver tissue structure and function. At the same time, also pose a serious threat to local farmers camel and human flesh food safety. Histopathology, the Bactrian camel liver lipoma is composed of four components by fat cells, stromal cells, blood vessels and fibers. According to the different proportions of each component, can be divided into two different manifestations: a form of expression is a lipoma is composed mainly by fat cells during mixed with a small amount of blood vessels and fiber content; another form of expression is in addition to fat cells (about 50%), and also includes a large number of mesenchymal cells and vascular components together constitute. The greatest change during mass cell components, various shapes, and these cells are neither fully equipped with fiber cells staining characteristics, not exactly have the muscle cell staining characteristics. The Bactrian camel liver fat tumor was invasive growth and expansive growth, especially invasive growth, no obvious capsule lipoma, causing serious damage to the surrounding liver tissue. The AgNOR staining shows, lipoma tissue fat cells and interstitial nucleus melanin particles is much higher than the number of fat cells in normal adipose tissue, especially the invasive growth of lipoma. Therefore, the Bactrian camel liver lipoma tumor cells with abnormal proliferation characteristics. The ultrastructural observation shows that fatty liver tumors, lipomas around the liver cell swelling, cytoplasmic edema, mitochondrial swelling, disintegration, cristae, and some even occur vacuolization. Endoplasmic reticulum membrane rupture, severe nuclear chromatin condensation, nuclear dissolution, organelle dissolution cell boundaries disappear. Partial liver sinusoidal gap within the collagen fibers, liver fibrosis. Lipoma tissue contains a large amount of fat droplets cell lipoma and pleomorphic cells containing particles of high electron density. This study showed that the sources of the Bactrian liver lipoma interstitium in the liver mesenchymal cells, especially mesenchymal cells of the blood vessels around the. Occurrence of lipoma very long-term intake of poison caused by chronic poisoning, poison on the one hand caused the injury (liver cells significantly degeneration and necrosis of the liver lobule structure), in particular, to the extent of the loss of the hepatic lobule surrounding more prominent, while also induce the occurrence of lipoma infiltration. In addition, comparative pathology research shows that there are similarities between the Bactrian camel liver lipoma and ordinary lipoma, angiomyolipoma, vascular lipoma difference, and each has its own characteristics.

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CLC: > Agricultural Sciences > Livestock, animal medicine,hunting,silkworm,bee > Animal Medicine ( Veterinary Medicine) > Livestock, poultry, wildlife diseases > Livestock > Camel
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