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[Background] in the practice of forensic science, language features injury severity often been identified disability rating is closely related to the identification of some of the injured due disguised, exaggerated, or the existence of the verbal dysfunction and makes use of existing Scale tool assessment the extent of the damage to the lack of reliability, explore reflect the objective and quantitative indicators of the injured Language dysfunction after traumatic brain injury has important application value. Domestic and international studies have shown that event-related potentials (event related potentials, ERP ) of certain components of language processing capacity is closely related, such as N 400 the P 600 < / sub>. The existing studies focus primarily is to explore the mechanisms of language processing, how by ERP technology surgery objective, quantified assessment of language processing capacity of injury and its value has yet to be in-depth study in the field of forensic science. Style 【Objective】 preparation suitable for patients with traumatic brain injury detection requirements the picture naming audiovisual cross sensory pathways the ERP Fan , for study in healthy volunteers and patients with traumatic brain injury, observed across sensory pathways speech processing ERP waveform characteristics and its correlation with the WAIS-RC for forensic identification of the speech function damage objective electrophysiological testing indicators. 【Methods】 using N e uroscan, the ERP instrument presents design their own picture - sound named paired the ERP seized measurement sequence, first subjects presented physical picture, and then give a right or wrong naming sound stimulus from the headphones. Make appropriate amendments to the stimulus program, according to the results of preliminary experiments, 40 healthy volunteers (26 men, 14 women) and 15 patients with severe traumatic brain injury (11 men, four women) were ERP inspection measurement and the Wechsler Adult Intelligence Scale (WAIS-RC) test, compared between the two groups of subjects the ERP Special levy ingredients and differences, analysis and correlation of WAIS-RC sex. Finally, aphasia testing, determine the mode experiments reliability. Results (1) through the picture - sound named paired ERP thorn excited normal volunteers pictures match the sound stimulus consistent and inconsistency can elicit N 1 P , N 2 , P 3 , N 3 , P 4 ERP into points, including the \The picture sounds mismatch stimulate the P 2 of latency, volatility increases (P lt; 0.01); N 3 00 amplitude negative change 450ms \ (2) in patients with traumatic brain injury picture - sound stimulus matching and wrong with also can elicit similar the ERP wave-shaped, compared with the normal group, paired stimulus N 2 , P < sub> 3 the N 3 latency extend approximately 30ms, N the 2 P 3 volatility negative variation (P lt; 0.01); mismatch stimulus P 2 N 2 P 3 latency very significant difference (P lt; 0.01), P 3 volatility there are very significant differences (P lt; 0.01). (3) Cross-modal the ERP wave shape of each component in the CZ FT7, FP , 2 , FZ, F4, F7, F3, T3, C4 point there are obvious waveform, which CZ, C4-point waveform differentiation best dual frontal and left temporal lobe play an important role in language function. (4) N 2 , N 3 incubation period and verbal IQ and IQ was low to moderate negative correlation (r = -0.45 0.35). (5) aphasia, the picture - sound paired stimulus 290ms-550ms bimodal waveform, N 300 wave and class N 400 effect \trauma group 2 times), N 300 -wave latency. Picture - sound mismatch stimulate only a single peak waveform. [Conclusion] picture - sound Cross-modal ERP detection paradigm \patients with traumatic brain injury \unimodal phenomenon bimodal change language processing capacity for damage has prompted. N 2 , N 3 incubation period and verbal IQ and IQ was low to moderate negative correlation, suggesting that specific components of language processing capacity of Cross-modal ERP have some relevance , can damage electrical objective detection language processing capacity as a forensic identification physiological reference indicators.
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