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The Quantitative Retrospective Study in Grade Level of Brain Dysfunction Induced by Head Injury (Ⅰ)

Author: DaiJianYu
Tutor: ZhangLingLi
School: Huazhong University of Science and Technology
Course: Clinical forensic medicine
Keywords: Brain dysfunction Classification Quantitative Discriminant analysis
CLC: D919
Type: Master's thesis
Year: 2009
Downloads: 42
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Abstract


Research background in clinical forensic traumatic brain injury, regardless of injury severity or degree of disability identification, often related to the evaluation of brain function, including mental retardation, mental disorders, cognitive dysfunction, and other damage consequences . However, due to the complexity of brain function, subject to a number of internal and external factors, and how to scientifically evaluate the degree of dysfunction Brain Injury has been the focus and difficulty of clinical forensic medicine research. There is no one way to make objective and comprehensive evaluation, especially for quantitative evaluation. Intelligence Scale Wechsler Intelligence Scale (Wechsler Adult Intelligence, WAIS) as a classic in the field of clinical and forensic applications widely become the main tool we evaluate IQ. But many to infer based on verbal response and performance of individual external behavior or results or evaluation of the extent of the damage their smart, results obtained by subjects subjective factors to some extent. In recent years, the event-related potentials (event-related potential, ERPs) electrophysiological studies by more and more attention began to be applied to the field of forensic science. ERPs is a psychological reaction to external or environmental stimuli, obvious psychological state, the reaction of the cerebral cortex cognitive status. This study identified the center traumatic brain dysfunction cases, the use of event-related potential results (P300), the Wechsler Adult Intelligence full-scale intelligence quotient the determination (IQ value), while reference such as age, time since injury, level of education, brain trauma degree discriminant function were statistically analyzed to establish a traumatic brain injury brain dysfunction degree of mathematical prediction model for forensic identification of such injury and clinical work to provide objective quantitative indicators. [Objective] To study changes in brain function in patients with traumatic brain injury event-related potentials, P300, IQ, age, time since injury, the relationship between the level of education, traumatic brain injury and other factors, the comprehensive utilization indicators, in patients with traumatic brain injury the degree of brain dysfunction quantitative classification. [Object method] The United States Nicolet production of Vikingquest of evoked potential to ERPs detection of 101 cases of brain injury, the amplitude and latency of the P300 component of the ERPs, the Wechsler Adult Intelligence Scale (Wechsler Adult Intelligence Scale, Revised in China, WAIS-RC) was measured IQ, the reference to a subject's age, time since injury, the degree of injury, level of disability, the pre-injury level of education, etc. were recorded. As a measure of the degree of brain dysfunction, was seized by the level of disability data collection, each index first significant test, after using a stepwise discriminant analysis discriminant function. Statistical description of the statistical methods used, analysis of variance, χ2 test, and stepwise discriminant analysis. [Results] to be seized by the P300, IQ, age, time since injury, two mandatory tests, traumatic brain injury level, occupation, whether surgical treatment, gender, pre-injury level of education as a variable stepwise discriminant analysis, the outcome variable P300 , IQ, age retained the remaining variables were excluded, draw three different discriminant equation 2, respectively assess mild, moderate a moderate two brain dysfunction, these variables establish discriminant equation correct rate of 70.5%. 【Conclusion】 P300, IQ, age and other indicators to assess the extent of brain dysfunction have a very important role in higher overall accuracy rate of this study is to establish the discriminant equation may be used as an objective assessment of cerebral dysfunction after traumatic brain injury in forensic identification indicator of the degree, but in the application process should be taken to exclude interference of subjective and objective.

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