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Analysis of the Change of Intraocular Pressure befor and after Laser in Situ Keratomileusis

Author: ZhuDongMei
Tutor: ZhuWei;WangKaiJuan
School: Zhengzhou University
Course: Epidemiology and Biostatistics,
Keywords: Myopic excimer laser in situ keratomileusis (LASIK) Intraocular pressure Central corneal thickness Curvature of the cornea Myopia
CLC: R779.63
Type: Master's thesis
Year: 2008
Downloads: 13
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Abstract


Objective: To investigate myopia non-contact IOP (Intraocular pressure IOP) measurement values ??and influencing factors, and excimer laser in situ keratomileusis (laser in siut keratom ileusis, LASIK) in the treatment of myopia surgery, postoperative non-contact IOP the change of the measured values ??and related factors. Method: take the excimer laser treatment of myopia in front of the right eye information 3325 cases (3325 right eye) and binocular anisometropia cases 277 cases, the application of statistical methods t test, analysis of variance, and correlation analysis, the study of central corneal thickness (Central corneal thickness CCT), corneal surface curvature, axial length, gender, age, refractive error and anisometropia with IOP. 164 cases (164 right eye) select more cases undergone LASIK treatment of myopia and review the complete data in the three months, respectively, before surgery, after one month, three months after each period the IOP (NCT measurements), CCT and The corneal curvature conducted the statistical analysis. Results: The mean of the IOP 16.21mmHg ± 2.73mmHg the (1mmHg = 0.133kpa). CCT 541.36μm ± 28.47μm, both positive correlation (correlation coefficient r = .4768, p <0.05). Corneal surface average Qu rate of 44.52D ± 1.11D positively correlated with IOP (correlation coefficient r = 0.1010, p <0.05). Increases with age, IOP decreased age ≤ 20 years of age the average IOP 16.52mmHg ± 2.86mmHg; 21 years old to 29 years old, the average IOP 16.20mmHg ± 2.84mmHg; 30-year-old to 40-year-old average IOP 16.08mmHg ± 2.84mmHg. 3 group analysis of variance significant difference (F = 4.4996, p = 0.0112). Increased, IOP upward trend with diopter, diopter ≤ 3.00D average IOP 16.08mmHg and ± 2.87mmHg; diopter 3.25D to 6.00D average IOP 16.20mmHg and ± 2.90mmHg; diopter 6.25D to 9.75D, mean IOP 16.46mmHg ± 2.79 mmHg; diopter ≥ 10.00D, average of the IOP 16.84mmHg ± 2.77mmHg. 4 group analysis of variance significant difference (F = 19.6636, p = 0.0001). No correlation between myopia IOP and axial length and gender. The anisometropia eye binocular IOP test the difference was not statistically significant (t = 0.5738, p = 0.5637). 3 months after LASIK, intraocular pressure 8.97mmHg ± 2.34mmHg corneal thickness 452.63μm ± 29.52μm intraocular pressure and corneal thickness positive correlation (correlation coefficient r = .3221, p = 0.0001); the cornea Qu rate 38.89D ± 1.23D changes in intraocular pressure, and central corneal thickness change was a positive correlation (correlation coefficient r = .4139, p = 0.0001); positively correlated with the corneal the flexor rate of change was positively correlated with IOP (correlation coefficient r = 0.2032, p = 0.0001); ( The correlation coefficient of r = 0.2865, p = 0.0001). Conclusion: The the myopia preoperative IOP and CCT positively correlated positively correlated with corneal flexor. The increased IOP decreased with age; elevated IOP rise with diopter; IOP and axial length and sex; anisometropia eye eyes IOP undifferentiated. IOP and CCT positively correlated positively correlated with the curvature of the cornea after LASIK surgery. The amount of laser cutting and flexor rate in the the IOP decline in the treatment of myopia after LASIK surgery decreases the amount of positive correlation. CCT important factor is the impact of the non-contact tonometer (NCT) IOP measurement value, with the change of corneal thickness, IOP measurement values ??change accordingly, must be considered in the analysis of IOP corneal thickness, especially excimer laser surgery After the eyes.

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CLC: > Medicine, health > Ophthalmology > Eye surgery and surgery > Retinal photocoagulation and laser eye surgery
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