Dissertation > Excellent graduate degree dissertation topics show

CT and MRI Demonstrations and Pathologic Analysis of Rabbits with Hepatic Neoplasm Treated with Cryoablation

Author: LinShaoHua
Tutor: LiuYuanShui
School: Taishan Medical College
Course: Medical Oncology
Keywords: rabbit liver neoplasm VX-2 carcinoma cryoablation magnetic resonance imaging tomography,X-ray computed
CLC: R735.7
Type: Master's thesis
Year: 2007
Downloads: 16
Quote: 0
Read: Download Dissertation


Objective:To describe the appearance of CT、MRI and pathology about rabbits with hepatic tumors treated with cryoablation on follow-up helical CT technology,to distinguish the radiologic-histopathologic correlation and characterize the imaging appearance of local tumor recurrence in the rabbit model.Methods:Hepatic cryoablation was performed in 17 rabbits with VX-2 tumors and in twelve healthy rabbits. Liver imaging was performed with CT、MRI one day prior to cryoablation and on the third day, seventh day,fourteenth day, twenty-first day, twenty-eighth day after cryoablation. Imaging findings were analysed comparatively with histopathologic finding.Results:1. all cryolesions exhibited arterial phase rim enhancement and noenhancement of central foci at CT,but showed diverse imging characters on the thirdly day,seventh day,fourteenth day,twenty-first day following cryoablation. and after 28days,normal control group has no longer enhancement sign; meanwhile tumors without cryoablated wholly show pearly rim enhanced imaging findings at the cryolesion periphery,and arterial phase pearly rim enhancement was growing bigger than before and further mergerd each other.2. All cryolesions exhibited various signal intensity characters at MRI imaging,but show diverse imging characters on the third day,and on the first、second、third week following cryoablation. and after four weeks, low signal intensity was seen at T2-weighted MR imaging at the cryolesion periphery if the tumor was totally ablated;meanwhile the other has high signal imaging findings. Areas of high signal intensity on T2-weighted MR images correlated with liquefaction necrosis、blood lake、granulation tissue and remnant tumor. High signal intensity findings on T2-weighted MR images should be evidence of residual tumor four weeks after cryoablation.Conclusion:1. Transverse contrast-enhanced arterial-phase and portal venous phase CT scans obtained four weeks after cryoablation show a large peripheral enhanced nodule that suggests recurrent tumor,which is helpful to distinguish correctly wether tumor was totally removed.2. High signal intensity findings shown at T2-weighted MR imaging at the cryolesion periphery were believed as an useful way to distinguish resiue and recurrent tumor four weeks after cryoablation.

Related Dissertations

  1. The Effect of Hemoperfustion in Different Time on the Proinflammatory Cytokines and Survival Time of Sepsis Rabbits,R459.7
  2. MRI Guoded Experimental Cryoablation of Rabbit’s Sciatic Nerve for MRI and Pathology Contrast Study,R445.2
  3. Research of the Correlation About the Expression of Mfap4 in Liver Fibrosis Tissues and Concentrations of Mfap4 in Peripheral Blood Associated with Liver Pathological Grade,R575.2
  4. Study of Triptolide Induced Hepato-toxicology by MS-based Metabonomics Approaches,R285
  5. Effects of Fix 6,7-furocoumarins on the Hepatic Microsome Cytochrome P2C9, 2C19 Activity in Rats,R965
  6. Stereoselective Metabolism of Tetrahydropalmatine and Its Effect on Hepatic Drug Metabolism Enzymes,R96
  7. The Expression of TH、 c-fos and Its Transcriptional Regulation in Locus Coeruleus and Adrenal Medulla on an Experimental Rat Model of Liver Depression Syndrome,R241
  8. The Impact of Atorvastatin- reduced Glutathione Combination to Anti-oxidation Action and Blood Lipid Level in Rats with Hyperlipidemia,R965
  9. The Supercritical Carbon Dioxide Extraction and Functional Quality Evaluation of Camellia Seed Oil,TS225.16
  10. Studies on the Molecular Mechanism of Anti-HBV Effect of Green Tea Extract Epigallocatechin Gallate,R285
  11. Effect of Oil and Different Initial Body Weight on Fatty Liver in Landes Goose,S835
  12. Nutritional Evaluation and Feed Effects of Solidago Canadensis in Rex Rabbits,S829.1
  13. Effect of in Ovo Leptin Administration on Hepatic Expression of Genes and Micrornas Involved in Cholesterol Metabolism in Broiler Chickens,S831
  14. Professor Wei Zhizhen clinical experience of academic thought and nourishing yin Pinggan Jiangni treatment of vertebral - basilar artery insufficiency of the study,R249
  15. The Study of Rabbit Bone Marrow Mesenchymal Stem Cells Separation Culture and Directional Differentiation,R329
  16. The Clinic Value of Diffusion Weighted Whole Body Imaging with Background Body Signal Suppression (DWIBS) Compared with hPET/CT,R445.2
  17. A Preliminary Study on the Regulation of Hepatoma Cell Biological Behavior by MCFP,R735.7
  18. Establishment of Feline Calicivirus (FCV) Reverse Genetics System Using RNA Polymerase Ⅱ and Expression of RHDV VP60 Gene,S852.65
  19. Effect of Leptin on Hepatic Expression and Activity of Iodothyronine Deiodinases in the Chicken,S831
  20. GC-MS Analysis of Endogenous Metabolites in Plasma of Police Dog after Aflatoxicosis,S858.292
  21. Retrospective Study on Pathological Results, Four Results of Liver Fiber, and TCM Syndrome Type of 164 CHB Patients,R259

CLC: > Medicine, health > Oncology > Gastrointestinal Cancer > Liver tumors
© 2012 www.DissertationTopic.Net  Mobile