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Plasma (1-3)-β-D- glucan detection of tumor chemotherapy fungal infection Diagnosis

Author: LiZuoZuo
Tutor: HuangYanChun
School: Xinjiang Medical University
Course: Oncology
Keywords: Deep fungal infections Plasma (l-3)-β-D- glucan Tumor Diagnosis
CLC: R519
Type: Master's thesis
Year: 2010
Downloads: 26
Quote: 0
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Abstract


Objective: through the plasma in patients with tumor after chemotherapy suspected fungal infection (1-3) - beta - D - glucan detection and fungus culture results of comparison, evaluation of plasma (1-3) - beta - D - glucan detection of tumor chemotherapy in patients with deep fungal infection diagnosed practical value. Explore suitable for tumor chemotherapy in patients with early detection technology of deep fungus infection. Methods: 124 cases of suspected fungal infections in plasma at the same time (1-3) - beta - D - glucan test specimens of the infection and fungi culture tests, and for statistical analysis. Results: 124 cases of suspected fungal infections (1-3) plasma - beta - D - glucan test positive rate was 52.4%, fungal culture tests positive rate was 44.3%, the two methods of detecting the difference was statistically significant (P lt; 0.005). Plasma (1-3) - beta - D - glucan, the sensitivity of detection results is 81.8%, 71.0%, positive likelihood ratio is 2.83, the negative likelihood ratio of 0.25. (1-3) conclusion: the plasma - beta - D - glucan detection with high sensitivity and specific degrees, and the diagnosis of deep fungus infection in patients with tumor chemotherapy has a practical value.

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CLC: > Medicine, health > Internal Medicine > Infectious disease > Fungi and actinomycetes infectious diseases
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