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The Development of Intermediate Frequency Micro-Electric Fields/Current Therapy Technique for Proliferative Diseases

Author: FangYu
Tutor: TangJinTian
School: Tsinghua University
Course: Nuclear Science and Technology
Keywords: Proliferative diseases IF Micro- electric field Micro-current
CLC: R454.1
Type: Master's thesis
Year: 2010
Downloads: 14
Quote: 0
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Abstract

Proliferative diseases, malignancy, also including benign prostatic hyperplasia, hyperplasia, the incidence was increased year by year and the trend of younger, serious impact on human health. Are in dire need of a new method of treatment for residual or recurrent tumor after surgery, and the tumor to radiotherapy and chemotherapy is not sensitive. In recent years, there are reports of the non-thermal effects of the electric field on the use of IF, abnormally dividing proliferation characteristics to effectively suppress the proliferation of tumor cells against tumor cells. However, with regard to the relevant specialized equipment R \u0026 D process is rarely reported. Another study also showed that the micro-current analgesic treatment of neurological diseases have a certain effect, no one has to explore its effect whether the treatment of malignant tumors and other proliferative diseases. IF alternating electric field shows great potential in the treatment of cancer and other diseases, especially for difficult surgical cure, and the chemotherapy the insensitive tumors is a promising treatment. In the same time, the intermediate frequency micro-current whether similar effects is also our hope that clear. In view of this, we have developed an intermediate frequency micro-electric field / current equipment, able to generate 25 kHz ~ 1.6 MHz sine wave, square wave and triangular wave signal, the peak-to-peak (Vpp) 24.6V ~ 32.8V. Hardware design, software programming, design and safety of three parts, the details of the research and development of technology in the device. The current strength of the electric field generated by this device at the same time of the simulation, the micro-electric field intensity between the 100 V / m ~ 101 V / m the magnitude of the current density of the micro-current size 10-1 A/m2 magnitude. Based on the research and development of equipment, we have carried out preliminary biological experiments as experimental subjects to malignant melanoma. The results showed that: the highest IF micro electric and micro-current in vivo tumor cell growth inhibition rate reached 27.11% and 82.16%, respectively; animals after micro-frequency electric field in vivo tumor volume reduced to 6.3% of the control group. Therefore confirmed the effectiveness of the device in the treatment of malignant tumors. View of other proliferative diseases also have similar abnormal cell division and proliferation characteristics of the technology has a large potential for treatment of other proliferative diseases (benign prostatic hyperplasia, mammary gland hyperplasia). The innovation of this paper reflects that: the first time the use of intermediate frequency micro-electric field treatment of cancer and other proliferative diseases; basic clear intermediate frequency micro-electric field treatment parameters of the mouse melanoma; 2. Introduction of the first intermediate frequency micro-current tumor therapeutic areas; 3. according to the similarities of the proliferative diseases and malignant tumors, proposed the idea of ??exploring the the IF electric field micro current treatment of other proliferative diseases.

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