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Objective: laboratory simulation environment , the healthy rats stimulus phlegm Yun- fat diet and smoked Law rat lung model , and model evaluation indicators . After the modeling , the spleen is the source of phlegm , lung sputum for the storage device essence of Chinese medicine theory , based on a deeper level of discussion and research . Methods: 48 healthy male Wistar rats were randomly divided into the following six groups : blank control group , model group group . 6 rats were placed under the appropriate conditions , respectively, at different stages giving different stimulus . Made film were observed during changes in the general situation of the rat , with particular attention to the oral and nasal secretions , cough , asthma , and other specific symptoms . In one day , 15 days , 29 days , 34 days to collect specimens , observed blood lipids , blood rheology , trachea and lung histopathology , MUC (5AC), oxidative stress factor , phenol red sputum test corresponding indicators of change . Application SPSS16.0 statistical software for statistical analysis of the experimental data processing and analysis of the results . Results: The from the physiological performance model rats can be heard significant airway sputum and cough , wheezing , against hair , body hair dry dull the extrados curl up to sleep , lack of exercise, unresponsive , thin stools and other symptoms . The histomorphological visible model rats trachea , the bronchial ciliated columnar epithelial cells were partially stripping , goblet cell hyperplasia, strong secretion of lung tissue inflammatory exudate , more obvious hyperplasia ; Immunohistochemistry showed the model rats MUCSAC secretion higher than normal group ; phenol red expectoration experimental observable to the the model rats phenol red excretion was significantly higher compared with normal group there are significant differences ; blood lipids and blood rheology shows model group increased significantly . Conclusion: pathology , immunohistochemistry , phenol red , such as testing a number of experimental indicators confirmed the success of this experiment made ??film . And physiological changes in rats and blood lipids , blood rheology changes further reveal Insufficiency correlation . \
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