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The single leaf clematis chemical constituents of

Author: YanMiao
Tutor: DuFangLu
School: Hunan University of Traditional Chinese Medicine
Course: Of Pharmacy
Keywords: Single leaf clematis Chemical composition β- sitosterol Daucosterol Mannitol Ursolic acid 1,8 - dihydroxy-3 ,5 - dimethoxy (mouth Hill) ketone Is tricosanoic acid
CLC: R284
Type: Master's thesis
Year: 2006
Downloads: 55
Quote: 0
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Abstract


Single leaf clematis (Clematis henryi Oliv.) Snow flowers ( \\Single Clematis located in the Yangtze River basin , downstream and provinces and regions south of the Yangtze River , clearing and detoxifying , blood swelling , qi analgesic effect . Pharmacological studies have shown significant analgesic sedation snow to open . Snow to open the study of the chemical composition at home and abroad is still empty by its chemical composition , extraction , separation and structural identification research , on the one hand, can provide a theoretical basis for its chemical classification ; the other hand, its pharmacological effects can better clarify lay a theoretical foundation to find a pharmacologically active ingredient , reasonable development and utilization of medicinal plant resources in Xiangxi single leaf clematis . The subject of the single leaf clematis ( Clematis henryi, Oliv ) carried out for the first time the study of the chemical composition . Herbs semolina was extracted with 70% ethanol and concentrated , using the the systems solvent extraction method respectively PE , CHCl3, EtOAc, extracted preliminary separation, and then repeated column chromatography on silica gel of the various parts , combined with the solvent method recrystallization treatment , separation and purification 7 compounds , the manager of a constant , spectral (UV , IR , 1H- NMR , 13C- NMR ) data analysis , identification of the six components . They are : β - sitosterol alcohol ( I ) , carrot the glucosides ( II ) , mannitol ( III) , bears the acid ( IV ) , 1,8 - dihydroxy -3,5 - dimethoxy ( ? ) One (Ⅴ), is tricosane acid ( VI ) are known compounds , six components are found from this plant for the first time .

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