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Of Pinellia and gastric particles of Objective To observe the clinical efficacy and safety of peptic ulcer, objective evaluation of the efficacy and safety of the treatment of peptic ulcer, and to explore its mechanism to guide its clinical application. Methods: determination of 1.1 cases of peptic ulcer cases the inclusion criteria (1) TCM diagnosis of epigastric pain, the TCM the dialectical spleen stomach heat, and the TCM symptom score more than 6 points; (2) comply with peptic ulcer diagnosis and the gastroscope ulcer with active diagnostic criteria by; (3) in the 18-65 years of age; (4) signed informed consent. 1.2 cases of atrophic gastritis, erosive gastritis, due to special reasons, stomach or duodenal ulcer (gastrinoma) exclusion criteria (1), gastrointestinal tumors, functional dyspepsia, malignant ulcers, the huge ulcer (> 2cm ~ 2), and may affect the Spleen the stomach heat Certificate or the evaluation of drug efficacy of various diseases (such as with a variety of serious chronic diseases); (2) pregnancy or breast-feeding women; (3) allergy the physique; (4) severe primary diseases of the cardiovascular, liver, kidney and hematopoietic system, the mentally ill; (5) does not meet the inclusion criteria, Failing medication not determine the efficacy or data insufficiency affect the efficacy or safety judges. The 1.3 TCM diagnostic criteria: epigastric fullness or part epigastric pain, and there is a history of repeated episodes. 1.4 TCM the standard master card: abdominal distention, or a combination of epigastric pain. Spleen symptoms: (1) the fatigue Shenpi (2) (3) appetite reduce loose stools soft (4) pulse slow stomach heat symptoms: belching or pantothenic acid (1) dry mouth (2) mouth pain (3) (4) tongue Yellow diagnosis: master card essential, together with the spleen, stomach heat symptoms can be diagnosed each 2-based card type. 1.5 Western diagnostic criteria: (1) long-term recurring cyclical rhythm chronic upper abdominal pain, may be associated with pantothenic acid, belching, nausea, vomiting and other symptoms; (2) in the upper abdomen may have limitations tenderness; visible with active ulcer (including gastric ulcer (GU), duodenal ulcer (DU) and composite ulcer) (3) endoscopy. 1.5.1 gastroscope diagnostic criteria: mucosal defects were round, oval, linear, irregular-shaped, flat bottom, neat edges, white fur or gray moss covering or a congestive mucosa scattered white moss, shaped Rushuang spot cream spots like ulcers. 1.5.2 the pathology diagnostic criteria: (1) to see the positive muscularis mucosa defects, and its next fibrosis submucosa fusion; (2) to see the regeneration of mucosal tissue, the mucosal epithelium was irregular room like the or tongue prominent interstitial loose or rich capillary tube; sometimes freshmen mucosa is relatively flat, but not inherent gland mucosa; (3) mucosa or renewable submucosal visible inflammatory granulation tissue; (4) showed obvious into pieces of necrotic tissue, rather than a small amount of inflammatory exudate; (5) endoscopy or X-ray examination revealed the presence of ulcers. 5 above, if (1), can confirm the diagnosis of gastric ulcer
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