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The protein chip the following gene chip another exciting places experimental technologies and methods , it has been widely used to study the interaction between the protein . Protein chip and microarray technology in the past few years has been considerable development , which implies a huge potential in the proteome function studies , clinical diagnosis , drug screening and testing , and disease detection . It is fast, easy , and can be achieved in a single experiment synchronous parallel detection of thousands of specific indicators . This technique in the diagnosis of human diseases such as leukemia , breast cancer , heart disease potential has been widely stimulated the interest of scientists from various countries . Currently, hepatitis B and C has triggered a worldwide major public health problem . Causative source of hepatitis B and C , respectively, for the hepatitis B virus and hepatitis C virus . Detecting comprises a number of species, mainly divided into the detection of gene amplification experiments and immunological markers for their markers . The former PCR method based operation of such methods , however , is more complicated, and the need to rely on the precious instrument , so the skill requirements of the experimenter , the experiment also higher costs . Immunological detection methods are usually more convenient and economic . Currently in clinical diagnosis , enzyme-linked immunosorbent assay method and rapid diagnostic test strip method is widely used . But these two methods also exist many drawbacks , mainly in that they are not synchronized parallel detection of multiple projects indicators . In our experimental study , we have established a lab-on-a-chip technology platform of a protein . Protein chip technology platform based nano gold and silver immunostaining zoom method of output signal , to achieve rapid , visually the purpose of observation . And synchronous detection of antibodies to hepatitis B and C , for example , to validate this technology . In the experiment, we were used glutaraldehyde and 3 - glycerol aminopropyltrimethoxysilane two kinds of different methods of ultra
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