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The Effect of OsteoSet in Repairing Bone Defects Due to Tumor

Author: ChengQian
Tutor: GuGuiShan
School: Jilin University
Course: Clinical
Keywords: OsteoSet-bone graft substitute Bone defect Autogeneic bone Allogeneic bone
CLC: R738.1
Type: Master's thesis
Year: 2006
Downloads: 14
Quote: 0
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Abstract


The repair of the bone defect has been thought a difficult problemof the orthopedics. The existence of these defect changes thepathological and biomechanics environment of the bone, eveninfection, function loss, often needing the bone transplantation. Theartificial bone has good living creature, bone conductibility, and highinduce of ossification activity, which can decline to solve, withoutside reaction and the virus. The artificial bone has great developmentforeground and clinical application value. Many literatures reportedthat CaSO4 applies to transplant in the bone, which is a kind ofinorganic bone material to conduct, and it can fuse, and has goodcompatibility. The OsteoSet is made from CaSO4, which naturalabsorption rate is in accordance with the new-born bone growth rate.Accompanying with the absorption of the grains, new-born bonesrecovered the bone structure. The OsteoSet is a kind of ideal material. 22 cases of bone defect due to tumor from 2004 to 2006 wereanalyzed clinically after repaired with OsteoSet, male 14, female 8.22 patients had no ache and unwell symptoms after operation.Everyone had been taken A-P X-ray. We could see the bone defectswere filled well. The mean follow-up was 7.23 months (range 6-9months), the OsteoSet absorbed well, without side reaction. Allpatients were satisfactory with the results. Only one of these patientsfractured at the 4th month. Because we did not give the good outsidefix, long-term dint stimulate induced the bone fracture, belong to thetired bone fracture, have nothing to do with the OsteoSet.The OsteoSet absorbed obviously at 4 weeks after operation. Atthe same time the bone trabecula built and the bone densityincremented. 97.1% OsteoSet absorbed at 12 weeks, 95.3% bone wasbuilt. 99.1% OsteoSet absorbed at 24 weeks after operation, more than80% bone cavities were filled with bone trabecula, new bone linkedwith the normal bone natural.The advantage of the OsteoSet is that natural absorption rate is inaccordance with the new-born bone growth rate. It can make bloodvessels grow with born cells of bone, at the same time absorbs,without side reaction. The OsteoSet has good living creature, boneconductibility, and high induce of ossification activity, which candecline to solve, without side reaction and the virus. So it is a kind ofideal material.

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CLC: > Medicine, health > Oncology > Sports Department tumor > Bone tumor
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