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BACKGROUND:The Traditional Chinese medicine (TCM ) "syndrome" is the basic of treatment, and is the essence of TCM. With the deeping in the research on TCM, revealing the essence of Syndrome is necessitous. Syndrome is the summarize of pathology and physiology of the different phases of different diseases, and since there are some common clinic manifestation and phathomechanism, there must be some common material basis. For several decades, the researchs on revealing the essence of syndrome had tentatively confirmed that there are some modern pathophysiological basis. According to the life central dogma, the genetype (DNA or gene) is the most primary and most essential matter of the life, mastering and confining the phenotype program (protein to cell to organism). Thus, the life phenomena, diseases, Chinese medicine syndrome can all have the most essential trace on the DNA or gene. TCM considers that the kidney stores the spirit, charges the development, growth, reproduction and fluid metabolism, which is the congenital foundation. The spirit in the kidney comes from the essential substance of reproduction of the parents, which is the primary substance for embryonic development. So, the kidney sprite serves the common identity with the genome DNA. And we consider that the relation of kidney
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