Dissertation > Excellent graduate degree dissertation topics show

The Expression of CD31, CD34 and CD105 in Squamous Cell Carcinoma of Tongue and Their Relationship with Lymph Node Metastasis

Author: ZhangYuYing
Tutor: SunChangFu
School: China Medical University
Course: Oral Surgery
Keywords: Squamous cell carcinoma of Tongue tumor Lymph metastasis CD31 CD34 CD105(Endoglin) Microvessel density(MVD)
CLC: R739.8
Type: Master's thesis
Year: 2006
Downloads: 287
Quote: 0
Read: Download Dissertation

Abstract


IntroductionSquamous cell carcinoma of tongue (TSCC) is the most common tumour in oral and maxillofacial malignant tumours which has high metastasis rate. It can lead to the neck’s lymph node metastasis in early times and distant metastasis lately. At present, many civil and external researches believe that the growth and metastasis of solid tumours are relative to the angiogenesis. Most scholars detect microvessel density (MVD) by means of the Van vascular endothelial markers such as CD31 ,CD34 nowadays. However, all of those markers can not distinguish the proliferating endothelial cells and the normal endothelial cells thoroughly. The update researches point out that CD105 can be expressed specially in the propagating vessels. In this research, we detect multiple antibodies including CD31 ,CD34 and the newest CD105 antibodies of different pathological grade, clinical stage and lymph node status, then we can deduce the relationship between the endothelial markers and the prognosis of TSCC patients.MethodThe experimental group includes 40 TSCC cases, and the contrast group includes 10 cases selected from the normal mucosa epithelium besides the TSCC. All the cases were stained by immunohistochemical S-P method, and then we a-dopt the Weidner’s method to count the tumor’s microvessel density ( MVD) marked by CD31 ,CD34 and CD105. All the data are described by x ± s and examined by T test and one —way analysis of variance, and they will be different in

Related Dissertations

  1. Expression of MMP-9 and p63 in Oral Squamous Cell Carcinoma and Clinical Significance,R739.8
  2. The Significance and the Dynamic Changes of Peripheral Blood Cd34+、 Cd166+ and the White Blood Cells after Hypertensive Intracerebral Hemorrhage,R743.34
  3. The Experimental Study of Semiconductor Laser Radiation and 5-FU Sustained Release Repressed Oral Malignant Tumor Cell,R739.8
  4. The Affection and Correlation of VEGF、 SDF-1 to the Homing of Bone Marrow Hemopoietic Stem Cells in Myocardial Infraction Area,R542.22
  5. GM-CSF in the Wound of Diabetic Rats BCL-2 Expression Levels,R644
  6. Study on Expression of Minichromosome Maintenance Proteins2、7 in Primary Squamous Cell Carcinoma and Cervical Intraepithelial Neoplasia and Its Significance,R737.33
  7. Clinical Analysis of Treating 4 Cases of Cervical Neuroendocrine Carcinoma,R737.33
  8. The Expression of IL-1β、CD34 and Their Significance in the Intervertebral Disc Degeneration of Subcutaneous Nicotine Injection of Rats,R681.53
  9. Association of β-catenin, Wnt1, Smad4, Hoxa9 and Bmi-1 with the Prognosis of Esophageal Squamous Cell Carcinoma,R735.1
  10. The Expression and Significance of VEGF in Esophageal Squamous Cell Carcinoma,R735.1
  11. Berberine Radiosensitizes Human Esophageal Squamous Cell Carcinomas by Downregulating RAD51 Expression,R735.1
  12. Inhibitory Effects of Curcumin Solid Dispersion on Tumors in Vitro and in Vivo,R285.5
  13. Repair of Buccal Mucosal Defects in Rats with Silk Fibroin Materials,R318.08
  14. Effects of Pulsed Electromagnetic Fields on Acute Hindlimb Ischemia Diabetic Rats in Microcirculation Angiogenesis,R587.2
  15. FOXP3(forkhead/Winged Helix Transcription Factor) and CD4~+CD25~+ Regulatory T Cells in Cervical Squamous Cell Carcinoma,R737.33
  16. The Expression of CD31、CD54 in Bleomycin-induced Lung Fibrosis of Rat,R563.1
  17. Promoter Methylation and mRNA Expression of TβRⅠ, Ⅱ Gene in Esophageal Squamous Cell Carcinoma,R735.1
  18. Expression and Prognostic Significance of PI3K in Esophageal Squamous Cell Carcinoma,R735.1
  19. Detection and Identification of Multi-index Aplastic Anemia and Myelodysplastic Syndrome,R55
  20. The Expression of Survivin and Ki67 in Esophageal Squamous Cell Carcinoma and Their Significance,R735.1
  21. The Clinical Study of Pemetrexed Combined with Cisplatin for the First-line Treatment of Advanced Non-small Cell Lung Cancer,R734.2

CLC: > Medicine, health > Oncology > Oral cavity, maxillofacial tumors
© 2012 www.DissertationTopic.Net  Mobile