|
Concave Magnolia officinalis Magnolia officinalis subsp . biloba (Reh.et Wils) Law Magnoliaceae magnolia species , medicinal dry skin , branch bark and root bark , widely distributed in our country , is an important traditional Chinese medicine in China , the warm Bitterpungent , has a lower temperature gas , dampness cited stagnation efficacy for anti-inflammatory sterilization , abdominal fullness , intestinal obstruction , phlegm, dyspnea full embolism, occupies a very important position in the clinical application . In this paper, a strong acid cation exchange resin extraction total alkaloids silica gel column chromatography and centrifugal thin layer chromatography separation and purification of the monomer compounds . 16 compounds were isolated from the the Sichuan Dujiangyan production Magnolia biloba dry skin , application of nuclear magnetic resonance , mass spectrometry , TLC and other means of identification of the structure of the 13 compounds , two compounds honokiol and magnolol 11 isoquinoline alkaloids : Liriodendron alkali (liriodenine), roemerine ( roemerine ) , lirinidine lysicamine the Swiss dry . spirit ( reticuline ) , Annonaceous alkali (anonaine), different Sasu Lin (isosalsoline), N- methyl isobutyl the the Sasu Lin the ( N - methylisosalsoline ) ,阿西米洛宾( asimilobine ) , N - drop nuciferine ( N - nornuciferine ) ] drop the nandina alkali ( nornantenine ) . Eight compounds apo Philippine class isoquinoline alkaloids , a simple benzyl isoquinoline alkaloids , two simple isoquinoline alkaloids . lirinidine, roemerine , lysicamine, different Sasu Lin , N - methyl isobutyl Sasu Lin , N - drop nuciferine drop the nandina alkali isolated from this plant for the first time . This article was first systematically studied alkaloids produced in Sichuan Magnolia biloba constituents , not only has a role in promoting the development of natural medicinal chemistry itself , and Chuan the advantage of producing concave Magnolia officinalis medicinal plant resources provide a theoretical basis for the development, utilization .
|