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Preparation, Formation Mechanism and Preventive Effect on Type Ⅱ Diabetes Mellitus of a Novel Functional Rice with High RS4 Content

Author: ZhangJinXiang
Tutor: LiBin；TangZuo
School: Huazhong Agricultural University
Course: Of Food Science
Keywords: Functional rice II diabetes RS4 Acetylation modification Safety Evaluation Eating sexual Metabolic syndrome
CLC: S511
Type: Master's thesis
Year: 2008
Downloads: 27
Quote: 0
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Abstract

Functional rice because of its unique advantages as a staple food, can easily interfere with nutritional deficiency or metabolic diseases, but has a tantalizing prospect; resistant starch because of their enthusiasm in the prevention and treatment of cardiovascular disease, diabetes, gastrointestinal cancer effect, has been accepted as a new type of high-quality dietary fiber; leading to excess backlog of early indica rice and eating poor. Improve the eating 早籼米 or functionality, and prepared to become a high resistant starch content of the staple food, whether it is for the response to the current global food crisis, or high-fat low-fiber \problem is of great significance. In this study, the use of low-value indica rice as raw material, the use of freezing enhanced mass transfer, acetylation modification of whole rice starch, prepared RS4 content of rice and its Eating sexual evaluation: take the instrument analysis tools to explore RS4 formation mechanism; preliminary safety evaluation of toxicology tests, and system evaluation based on high RS4 functional rice II diabetes prevention. The main findings are as follows: 1, rice and Na ₂ the CO ₃ solution in accordance with the ratio of 1g: 3ml, frozen after 6h at 30 ° C, pH10, liquid and materials than 2.0 mL: 10g, reaction 5h, the highest content of 73.19% and a high RS4 rice can be prepared. And the small scale of the single factor RS4 content of all samples were> 53% acetyl content of 0.59% -5.30%. After statistical analysis, the RS4 content of acetyl content without significant correlation, suggesting that the actual production can choose more environmentally friendly, mild economic conditions. Slow digestion of modified rice starch content also increased after dry heat treatment, RS content were significantly elevated. 2, using FT-IR, SEM, XRD, DSC explore the the RS4 formation mechanism. The results show that the force permeation in the freezer, some of the crystalline regions is destroyed by growth of ice crystals, and strengthen the Esterification, particles rice starch molecules can occur in low degree of substitution, and the substituent is not limited to the amorphous region of the crystallization region also react. The hydrolysis of α-amylase due to mass transfer hindered substituted lower particle density inner layer, mainly for the unsubstituted portion of the amorphous region, thereby forming a hollow structure of a particle. Little change in crystal structure of the low degree of substitution of starch, only when acetyl content up to 3.25%, partially microcrystalline (2θ18 °) is a little destruction, the decline in the degree of crystallinity, crystal melting heat required down gelatinization temperature drops The gelatinization enthalpy also showed reduced. SEM, XRD, DSC prompted low degree of substitution of acetylated starch anti-enzymatic hydrolysis, the functional groups of the crystalline regions of closed role. 3, high RS4 rice gel consistency, alkali, and RVA, TPA determination and so their eating than the original rice improvement setback is reduced to about 3/4, indicating high RS4 rice after cooking is more resistant to aging. Reasons but the starch structure destruction, Determination of the amylose content is no longer suitable as eating evaluation key indicators; rice particles thoroughness of the change, making the cooking characteristics can not the effective evaluation RS4 rice cooking quality, so evaluation modified rice Eating should create a new evaluation. 4, the acute toxicity test confirmed that the high RS4 content rice is a non-toxic, 30d feeding experiments high RS4 content rice growth and development of long-term consumption of animals, hematopoietic function, and liver and kidney function no harm. The estimated maximum effect dose greater than 50g/kg, is the safety of food. High RS4 content of rice may have the amino acid sparing effect, the increase in body weight of rats; experimental dose can be reduced TC (total cholesterol), TG (triglycerides) and BUN (blood urea nitrogen) levels, with kidney secretion nitrogen reduction burden protect the kidneys to regulate and improve the function of the lipid metabolism. 5, add high RS4 content of rice feed intervention type II diabetic model rats RS4 reduce postprandial blood glucose, to reduce Glycogenolysis, reduce hepatic glucose output, improve insulin sensitivity, Lipid Metabolism II diabetes can improve and glucose metabolism disorders. The histopathological observations indicate that the positive preventive role of the RS4 high sugar high fat diet-induced fatty liver.

Preparation, Formation Mechanism and Preventive Effect on Type Ⅱ Diabetes Mellitus of a Novel Functional Rice with High RS4 Content

Abstract

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