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Objective To observe the status quo of the Shihezi and surrounding areas Kazakh and Han population the prevalence of MS, explore of IL-6 and hsCRP Kazak and Han MS. Take cluster sampling method to extract the Shihezi City and the surrounding area residents 20 years old and above Kazakhs in 1444 and Han 2206, conducted a questionnaire survey, physical examination and blood biochemical parameters. Randomly selected case-control study of 213 cases of MS patients Kazak 195 cases and Han as the case group, and select without metabolic abnormalities Kazakh, the same crowd of 120 cases and 201 cases Han as a control group, and the determination of IL-6 and hsCRP FINS level. IL-6 was measured by ELISA, hsCRP assay turbidimetric immunoassay, FINS was measured by radioimmunoassay. With Epidata3.02 to establish a database, data analysis using statistical software SPSS13.0. Results 1.MS prevalence: diagnostic criteria according to the IDF, the Kazakh prevalence of 32.5% (29.0% male, 34.9% female), Han 25.3% (23.0% male, 26.9% female), standardized Kazakh suffering disease rate of 21.11% (19.11% male, 23.4% female), Han 20.65% (19.37% male, 22.75% female). 2.MS the prevalence of the individual components: Kazakh abdominal obesity rate of 54.5%, or Hans 43.4% (P lt; 0.05); the Kazakh blood pressure abnormal rate of 51.0%, or Hans 50.6% (P lt; 0.05) ; Kazakh fasting glucose abnormality rate was 33.5%, or Hans 25.0% (P lt; 0.05); the Kazakh high TG was 19.6%, Hans 34.5% (P lt; 0.05); the Kazak low HDL-C was 38.1%, Han was 30.8% (P lt; 0.05); Kazakh dyslipidemia was 60.6%, Han was 62.1% (P lt; 0.05). Serum IL-6 levels: Kazak and Han MS group were significantly higher than that in control group [(1.98 ± 0.52,1.71 ± 0.61, P Ha lt; 0.05); (1.50 ± 0.45,1.30 ± 0.52, P Han lt; 0.05)]. Kazakh serum IL-6 levels higher than the Han. Serum hsCRP level: Kazak and Han MS group were significantly higher than that in control group [(0.46 ± 0.34,0.19 ± 0.27, P Ha lt; 0.05); (0.27 ± 0.26,0.08 ± 0.22, P Han lt; 0.05) ]. Kazakh serum hsCRP level higher than that of the Han. With the increase in the number of abnormal metabolic components, Kazak and Han population serum IL-6 and hsCRP water average gradually increased. 6. Analysis: In the MS group, Kazak and Han hsCRP and IL-6 into a positive correlation. Kazakh serum IL-6 and hsCRP levels and age, body weight, BMI, WC, WHR, SBP, DBP, TG, FPG, LDL-C, TC, FINS and HMOA-IR levels into a positive correlation with height and HDL-C level is negatively related; Han serum IL-6 and hsCRP levels and body weight, BMI,, WC, WHR, SBP, the DBP, TG, FPG, LDL-C, TC, FINS and HMOA-IR levels positively correlated with HDL-C levels were negatively correlated, Han serum IL-6 levels positively correlated with age. Conclusions. Xinjiang Kazak and Han MS prevalence rate higher than in Han, Kazak, higher in women than in men, including Kazakh women the highest prevalence of MS. Kazak and Han MS serum IL-6 and hs-CRP levels significantly increased, suggesting the presence of low-grade chronic inflammation, and the Kazakh serum IL-6, hsCRP level was significantly higher than the Han. 3. Kazak and Han serum IL-6, hsCRP levels with obesity, insulin resistance, lipid abnormalities associated. Kazak serum IL-6 and hsCRP level of MS closely than Han.
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