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Research of Lung Function of Multi-slice Spiral Computer Tomograph in Quantitative Imaging Technology
Author: ChenHuai
Tutor: ZengQingSi
School: Guangzhou Medical College
Course: Medical Imaging and Nuclear Medicine
Keywords: COPD Tomography , X - ray computed Pulmonary function tests Computer software Quantitative
CLC: R563.9
Type: Master's thesis
Year: 2010
Downloads: 22
Quote: 0
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Abstract
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The first part of the multi-slice spiral CT quantitative imaging technology pulmonary parameters applied research Objective: To evaluate MSCT pulmonary function parameters with conventional lung function parameters correlation to determine MSCT pulmonary function parameters normal. Materials and methods: normal volunteers 30 cases through routine lung function check and MSCT check at the end of the maximum inspiratory and maximum end-expiratory breath-hold scan all data through the lung computer aided inspection system software to analyze the data obtained with the lung function tests (PFT) correlation analysis. Results: by MSCT scan obtained with normal lung air content, maximum inspiratory volume (Vin) and forced expiratory volume (Vex) and PFT resulting total lung capacity (TLC) and residual volume (RV) good (r = 0.904, P lt; 0.01; r = 0.743, P lt; 0.01), Vex / Vin and RV / TLC also has a very good correlation (r = 0.736, P lt; 0.01) (, Vin-Vex) the MVC also good correlation (r = 0.854, P lt; 0.01). The deep inspiratory mean lung density at the end of (- 879.51 ± 32.82) HU, unit volume density (0.1201 ± 0.0327) g/cm3 deep end expiratory mean lung density (-688.14 ± 62.38) HU unit volume density ( 0.3119 ± 0.0612) g/cm3. 4, conclusion: of MSCT pulmonary function tests obtained from a series of quantitative parameters and pulmonary function data with good correlation, its ease of operation, objectivity, can become one of the lung function in patients with clinical kinds of new effective detection method. Part II: multislice CT quantitative imaging in COPD Objective: evaluate MSCT quantitative imaging parameters with conventional lung function parameters correlation, analysis of patients with COPD and normal volunteers MSCT quantitative parameters compared to determine COPD patients MSCT clinical feasibility of quantitative imaging parameters. 2 Materials and Methods: COPD patients 20 cases by conventional pulmonary function tests and MSCT is the largest end-inspiratory and end-expiratory breath-hold scan all data through the lungs computer aided inspection system software to analyze the resulting data and lung function Check (PFT) correlation analysis, and the data were analyzed and compared with normal volunteers. Results: Vex / Vin and RV / TLC significant correlation (r = 0.90, P lt; 0.01), maximal inspiratory volume (Vin) and forced expiratory volume (Vex) and PFT resulting total lung capacity (TLC ) and residual volume (RV) is also very good correlation (r = 0.70; 0.81, P lt; 0.01), (Vin-Vex) and FVC also good correlation (r = 0.76, P lt; 0.01). EV-910 deep expiratory FEV1/FVC% good correlation (r = -0.84, P lt; 0.01). PI-910in, PI-950in PI-910ex, PI-950ex have a good correlation with FEV1 and FEV1/FVC% to breath better phase, in which the PI-910 ex related sex is better (r were -0.86, -0.85, P lt; 0.01). Deep end-inspiratory lung volume (5318.15 ± 1200.74) ml, mean lung density (-898.04 ± 35.36) HU unit volume density (0.102 ± 0.035) g/cm3, no statistically between the three normal volunteers significant (P greater than 0.01). Deep end-expiratory lung volume (3878. 21 ± 1202.75) ml, mean lung density (-855.04 ± 50.41) HU unit volume density (0.144 ± 0.051) g/cm3 statistically between normal volunteers significant (P less than 0.01). 4 Conclusion: MSCT pulmonary function tests can be a good assessment of the situation of patients with COPD, can provide an objective basis for clinical diagnosis.
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