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A subject of cotton horse Guanzhong Pieces processing technology, quality standards and stability studies. Intends to achieve standardization of processing technology, and scientific quality standard. A proven, reliable technology with the feasibility of large-scale production. Expected Pieces valid for two years. Specific work are as follows: product yield, out anointed rate, total phenolic content, extract as an indicator, cotton horse the Guanzhong different cutting process inspection results show that the intrinsic quality of the highest irregular cut into thick slices, and \By orthogonal test method, temperature, time, turning speed as the investigation factors investigated fried carbon process. With the deepening of the degree of fried carbon, total phenolic and cotton the horse crassirhizoma prime content showed a decreasing trend, not as orthogonal test evaluation, then select pharmacodynamic study - clotting time as the evaluation index, screening the most good process. Combined with large actual production, the development process: the pot temperature 350 ℃, dosage, 7-minute stir fry, fried medicine machine speed 23 rev / min. 10 batches of test samples in the validation, the process is stable. \Quality standards, determine the the cotton the horse crassirhizoma moisture limit of 12%, raw products, carbon products total ash limits were 7.0%, 7.5%, acid insoluble ash limits were 1.5%, 1.3%, extract limits were 20%, 16%. Study the heavy metal content of 10 ppm or less, the the arsenic salt content of less than 1ppm, pesticide residues were not detected. And to establish a method for the determination, the determination by HPLC the cotton MA Cyrtomium-prime content, identified by Health products, carbon products, cotton horse Cyrtomium pigment content limits were 2.5%, 1.5%; Determination of total phenolic content by UV method, identified by Health products, carbon products in the total phenolic content limits were 6%, 8%; tannin content determined by UV, results showed that the tannin content decreased fried carbon. 2 cotton horse crassirhizoma, processing technology and quality standards research on the basis of antibacterial activity and clotting time as the index, the market mainstream varieties Osmunda japonica, the single bud Woodwardia Guanzhong cotton horse Guanzhong processed products were compared Research results show that the three herbs processed products have antibacterial activity, the antibacterial activity of different strains each. The three herbs processed products have clotting effect, a single bud role of Woodwardia Guanzhong strongest,, cotton horse Guanzhong followed Osmunda japonica followed. Osmunda japonica, the single bud Woodwardia Guanzhong found clinical prescription basis. The results also showed that the antibacterial activity of raw products significantly stronger than carbon products, clotting effect of carbon products was stronger than the raw product, the raw product is longer than the insecticide, detoxification, the carbon products longer than hemostatic traditional concocted theory is a scientific.
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