Dissertation > Excellent graduate degree dissertation topics show

The Study of Changes of Serum Vasopressin、Prolactin and Nitricoxide in Patients with Cerebrovascular Disease

Author: ZhuPing
Tutor: LingZongXiu
School: Chongqing Medical University
Course: Emergency Medicine
Keywords: Cerebral hemorrhage Cerebral infarction Nitric oxide Arginine vasopressin prolactin
CLC: R743.3
Type: Master's thesis
Year: 2004
Downloads: 76
Quote: 0
Read: Download Dissertation


Objective:To find out the clinical value of changes of AVP, NO and PRL in serm in different periods、intracranial pressure、area of infarction and different volume of hemorrhage in patients with cerebrovascular disease.Methods: Choice 50 cases with infraction, 50 cases with hemorrhage and 30 comparative cases. All cases were measured the intracranial pressure. The diagnoses of cases were in accordance with the criterion of cerebrovascular disease in 1995, without other serious physical disease. They were divided into two groups according period after onset: acute phase: 1 hour – three days after onset ; recovery phase: > 21 days after onset. According to different levels of consciousness and muscle power ,They were divided into lightly group and serious group . They were divided into two groups by different CFP(CFP>2.05kpa; CFP<2.05kpa).The patients were divided into three groups according the result of CT: large infraction zone ; multitudes of infraction zones and small infraction zones. The patients were also divided into three groups by volume of hemorrhage. ( <20ml; 20~40ml; >40ml). <WP=10>Results: The levels of NO, PRL, AVP with ACVD were higher than comparative group (p<0.05), which were closely correlated with progressing time、infraction rang of CI、volume of hemorrhage and the clinical prognosis. The levels of NO, PRL, AVP in most of patients with CH, CI be down to normal in recovery phase. While The level of AVP in a few infracted cases with dysnosia was lower but PRL was higher than comparative group conversely. Conclusions:1. The levels of AVP, NO, PRL increased in ACVD, and were closely correlated with severity of illness, the length of period after onset, ICP, area of infraction and volume of hemorrhage. They may involed in the pathophysiology of brain damage after CI, CH .The changes could be as reference criterion of severity and clinical prognosis. 2.AVP was lower than normal and PRL continued to high level in vascular dementia patients in recovery phase. It is seemed to relate to the pathophysiological processes of VD and these cases might be treated and prevented by AVP or DA.3.The increasing of plasma level of AVP, NO, PRL in ACVD and the damage to brain suggested that those cases may be cure by iNOS-inhibitor, nNOS-inhibitor, AVP-receptor-antagonist, PRL-receptor- antagonist and the monoclonal antibody of them .

Related Dissertations

  1. Studies on the Effects of Exogenous Nitric Oxide on Rice under Cadmium Stress,S511
  2. A Control Study about Small Bone Window Hematoma with Hematoma of Endoscopic in the Basal Ganglia Intracerebral Hemorrhage,R651.11
  3. Tissue-engineered Construction and Preliminary Implantation Study of Diamond-like Carbon Films for Artificial Mechanical Valve Applications,R654.2
  4. Kinase Activities Analysis and Localization of ZmCCaMK Induced by Abscisic Acid in Leaves of Maize Plants,S513
  5. Therapeutic Effect and Mechanisms of Derived Mesenchymal Stem Cells in Intracerebral Hemorrhage Rat,R743.34
  6. Effects of Cold-adaptation Swimming on Hemorheology and Quantity of NO and NOS in Aorta of SD Rats in Acute Cold Water Stress,R87
  7. Changes and Roles of Plasma Hydrogen Sulfide in Elderly Patients with Ischemic Heart Failure,R541.6
  8. The Relationship between Exhale Nitric Oxide and Serum Eosinophil Cationic Protein, IL-13, IL-8 in Acute Asthma Exacerbation,R562.25
  9. The Relationship of Serum Adiponectin、Nitric Oxide Synthase and Carotid Atherosclerosis in Patients with Acute Cerebral Infarction,R743.33
  10. The Clinical Study on Relationship between Plasma Homocysteine Levels and Recurrent Cerebral Infarction,R743.3
  11. Clinical Research on Cognitive Event-related Potential N300 in Acute Cerebral Infarction,R749.1
  12. Berberine on serum levels of superoxide dismutase and malondialdehyde levels in,R743.33
  13. Integrative treatment of acute hypertensive cerebral hemorrhage,R743.3
  14. Hyperaccumulators Solanum nigrum (Solanum nigrum L.) tolerance and accumulation of Cd physiological and molecular mechanism of,X173
  15. Soft tissue crush injury in rats induced reactivity of isolated thoracic aorta changes,R686
  16. MWCNTs and ZnO / SnO 2 Composites and NO gas research,TB33
  17. Study of Image Lesion Patterns and Collateral Compensation to Cerebral Infarction Patients with the System of Ipsilateral Internal Carotid Artery Stenosis or Occlusion,R743.3
  18. Clinical Analyses of 148 Cases of Cerebral Infarction in Young Adults,R743.3
  19. The Mechanisms of Propofol-induced Relaxation on Isolated Thoracic Aorta Rings in Rats,R614
  20. In Vitro Study of Theeffects of Fullerol on the Hippocampal Synaptic Plastisity,R741
  21. The Effect of Different Concentration of Urokinase on Stereotactic Aspiration of the Rabbit Intracerebral Hematoma and the Expression of the Heme Oxygenase-1,R743.34

CLC: > Medicine, health > Neurology and psychiatry > Neurology > Cerebrovascular disease > Acute cerebrovascular disease ( stroke)
© 2012 www.DissertationTopic.Net  Mobile