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The doctrine of of the Viscera is the the the of the the core of the contents of of of the Chinese medicine practitioners theoretical system of, is the a typical representative of of the the the Sino-Medical the overall concept of and the the System Viewpoint of. System of the Viscera in essence is one in order to the five internal organs as the core, contact the the human body Six Hollow Organs, five-body, facial features, Five Khieu, Pentatonic, the five-chi, and the the natural world five parties, Five quarter of, five gas, five-color, five-flavored, five, etc. elements of while the the formation of of the as the main the characteristics of in order to the the integrity of large system. Therefore, the the research of the the doctrine of of the Viscera, the inevitable you want to people placed on the the the natural as a whole, that is, the the framework of of the the time and the space of the to go taken into account. 1 the purpose of: in order to the the kidney of the to Chinese medicine, \the the of the the feasibility of ideas of and its the scientific nature of of of the Experimental Study on, so as to the the research of the doctrine of of the TCM possession of elephant of to to provide the the the the support of on the in the experimental. 2 method: 2.1 overall design: pineal gland is the an intermediary of the the light stimulation with the the the body reaction of the, it on the one hand to accept the the retina-incoming illumination signal, on the one hand, this the rhythmic the secretion of of The signal transformation for the of melatonin and, on the the the whole body multi-system, were multi-organ in generate the adjust the; The in the the the process of of in the cells signal transduction, the the of c-fos and the c-jun to play a forward to important the role of, is the the as a bridge of will be the the cytoplasm of the event with the gene of transcription Contact up and the, can be used as that the multi-bar signal transduction the the a sign of of the pathway activities state it . Of the experimental through the the to removal of the pineal gland in order to blocking its an intermediary the role of., The to observe the c-fos and the c-jun mRNA the next hypothalamus - pituitary - thyroid-axis of the seasonal expression of law of, and interpretation of the generate the mechanism of the the the intrinsic regulation and control of the to this rule. 2.2 Experimental animals: SD rats, male ,180-200 g or / only. Were randomly divided into the physiological group, model group, and pseudo-surgery group; natural illumination, and freedom of intake of potable water, the room temperature rearing; in the to the each year the winter solstice, implementation of the pineal gland the summer solstice a few days ago a month, respectively, on the to the model group and the the pseudo-surgery group rats surgery for the removal and pseudo-surgery , Period to to Sunday postoperative be rearing, were sacrificed by decapitation, Remove the hypothalamus, the indicators of the pituitary, thyroid gland to the 备 measured. 2.3 detection method: detection adopt the organizations in situ hybridization Law. A 2.4 of analysis of method: the use of image analysis professional image analysis software 6.0; the statistically analysis of to to use the the SAS8.2 Statistics analysis of software. 3 the results of: rats under the hypothalamus, pituitary, the thyroid c-fos and the c-jun mRNA has a winter expression strongly, the expression of more than the amount, summer expression weakened, expression a less the law of; line that the the pineal adeno-has undergone surgery to remove, Such laws were disappeared . The expression of the the rat tissues of the model group c-fos and the c-jun mRNA to during the winter months to lower than the the the the physiological group and the the the pseudo-surgery group, to higher than the the physiological group and the the the pseudo-surgery group in the the summer; the the the the physiological group of of the the same organization of the the same season and the the the pseudo-surgery group between the expression no difference in; made no difference in of the the the model group of of the the same organization during the winter months and the the summer the expression of. 4 Conclusion: The experimental results support the \transformed for the the the the the key to of the the body chemical signal, from the a sense said to be the the as a bridge of communication between man and nature; the The experimental the results of also show that the that the the the the the adaptability of the regulation and control with the cells of of signal of of the the the main bone of of the \Therefore think that, research Chinese medicine practitioners from the the the angle of of cells signal transduction \further in-depth the research.
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