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Objective: through the study of diabetes (Diabetes Mellitus, DM) and vascular lesions in patients with serum high sensitivity C-reactive protein (high sensitive C-Reactive Protein, hs-CRP) level, and DM vascular lesions in patients with hs-CRP and TCM-relations discussed serum hs-CRP and diabetic vascular lesions in the development of the relationship between hs-CRP and diabetic vascular disease TCM-. Methods: This study selected 66 diabetic patients without vascular disease, 30 cases and 36 cases of vascular lesions, 30 cases of the normal control group. Diabetic patients without vascular lesions classified as Group A; vascular lesions of diabetic patients classified as Group B, and then the 36 patients with vascular lesions of diabetic group (A) is divided into the blood stasis Group and hot and humid poison Sheng TCM syndromes syndrome group. Records of patients in each group of age, gender, height, weight, duration, diabetes and other complications, and detection of a group of patients with systolic blood pressure (SBP) and serum hs-CRP, fasting plasma glucose (FPG), fasting insulin (Fins), glycosylated hemoglobin (Hba1c), cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL), high density lipoprotein (HDL) levels, and then among the groups above indicators were statistically analyzed. The statistical methods used for the SPSS13.0 package handling data. Results: The serum hs-CRP levels in the normal control group, DM vascular lesion group (A), between DM vascular disease group (B) are significant differences, and A, B two sets of hs-CRP water were higher than normal control group (P lt; 0.01), group B hs-CRP is higher than in group A (P lt; 0.01); through A, B between the two groups of other factors comparison, the systolic blood pressure (SBP), fasting insulin (Fins) and the duration of the significant differences; stepwise regression analysis in DM patients screened systolic blood pressure (SBP), body mass index (BMI), duration, and fasting insulin (Fins) four indicators and changes in hs-CRP levels close positive correlation between the size of the arrangement: Fins gt; the the SBP gt; BMI gt; course of the disease; blood stasis group hs-CRP levels and the heat toxin Sheng syndrome group two independent samples T-test, P value = 0.018 <0.05 significant difference, the heat toxin Mason syndrome group (8.02 ± 3.52)> blood stasis group (5.85 ± 1.54). Conclusion: as an inflammatory reaction of the most important and most sensitive marker of increased hs-CRP levels and diabetes development is closely related to, in order to verify that diabetes is a chronic low-grade inflammation state hypothesis, hs-CRP group B than Group A (P lt; 0.01) further illustrate the increase in the level of inflammation involved in the development of diabetic vascular disease; systolic blood pressure (SBP), body mass index (BMI), duration, and fasting insulin (Fins) four indicators hs- close positive correlation between changes in CRP levels, SBP, Fins, BMI is an important factor for diabetic vascular disease and accelerate the process of atherosclerosis, also suggest that hs-CRP may serve as a bridge in the process of the development of diabetic vascular disease role; blood stasis group, with the heat toxin Sheng syndrome group differences hs-CRP levels significantly, and heat toxin Sheng syndrome group was significantly higher than the blood stasis group, diabetic vascular disease patients prompt card is hot and humid poison Sheng Qingrejiedu dampness on the basis of lower hs-CRP levels may play an important role in the treatment of type 2 diabetes, vascular lesions. To sum up, monitoring and reduce hs-CRP levels is one of the effective measures for the prevention and control of DM patients with vascular lesions and progress, a serum hs-CRP levels greater standardization of diabetic vascular disease TCM syndrome typing objective indicators.
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