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Preparation and Characterization of Ag/HA Composite Coations by Sol-gel Dip Coating and Electrochemical Deposition on Porous Titanium Surfaces

Author: QuJie
Tutor: LuXiong
School: Southwest Jiaotong University
Course: Materials Science and Engineering
Keywords: Hydroxyapatite Porous titanium Sol - gel Electrochemical deposition Antibacterial Biocompatibility
CLC: R318.08
Type: Master's thesis
Year: 2011
Downloads: 87
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Abstract


Titanium and titanium alloys in the biological environment, with good mechanical properties, corrosion resistance and biocompatibility, has been widely used in the manufacture of implantable devices and biomedical devices, such as the hip, knee and dental implants body and so on. However the metal titanium demonstrate biologically inert human bone tissue difficult it directly. In addition, the bulk metallic titanium implant Young's modulus (90-110GPa) with the body's natural bone (0.3-30 GPa), the Young's modulus difference more. This may cause severe stress to bend and eventually cause bone resorption, implant loss and other problems. If the titanium implant system made porous by adjusting the porosity of the porous titanium can be indirectly regulating the Young's modulus of the implant, so as far as possible with the body's natural bone tissue close. Further, studies show that, compared with the bulk implant, the bonding strength of the porous titanium and bone to be much higher than the binding strength of massive implants and bone. This is because the biological nutrients can pass through freely inside the porous titanium and provide nutrients for bone tissue ingrowth within the porous titanium favor porous titanium internal length is Life organization. This is similar to the combination of the inner lock structure will significantly improve the bonding strength of the porous titanium and bone. If prepared in the surface of the porous titanium having the biological activity of the hydroxyapatite (HA) coatings, and nano-silver (Ag) to give the coating some antibacterial ability can be obtained compatible with the excellent mechanical properties, anti-inflammatory and biocompatible biomedical implant materials. The study prepared by powder metallurgy porous titanium foam copy. Titanium powder particle diameter of 30μm, dried leaching pulp after the first pass through the 400 ° C muffle furnace sintering to remove the polyurethane foam. Go through 2 hours 1300 ° C vacuum sintering can get a higher rate of the strength and the through hole, the aperture size is ideal porous titanium bracket. Currently, many methods of preparation of Ag / HA composite coatings, such as plasma spraying, magnetron sputtering method. However, most of the methods is a linear method, can not be in the complex shape of the substrate (eg, porous titanium) inside and outside surfaces at the same time preparing Ag / HA composite coatings. Sol - gel extraction method and pulse electrochemical deposition method are smooth in the preparation of the inside and outside surfaces of the porous titanium uniform continuous Ag / HA composite coating method. The sol - gel extraction method, adding a different quality in 150ml of hydroxyapatite gel silver nitrate dissolved fully leached porous titanium. Dried and sintered at 600 ℃ can be obtained Ag / HA composite coating. Pulse electrochemical deposition process, the electrolyte [Ca2] = 5.0mmol / l [PO43-] = 3.0 mmol / l; pH = 4.0; deposition time = 2 hours; pulse potential =-2V. Quality in the electrolyte by adding silver nitrate to control Ag / HA composite coating nano silver particle content. Detected by scanning electron microscopy, X-ray diffraction, EDS spectrometer such, both methods are able to simultaneously prepare a uniform continuous composite coating the porous titanium inner and outer surfaces. The resultant coating thickness of sol - gel extraction method, about 30μm, the coating was loose shape; pulse electrochemical deposition resulting coating thickness is maintained at about 10μm, the coating is more compact overall. The detection of the EDS found that the two methods in the resultant coating nano silver uniform in vitro cell culture experiments, sol - gel extraction method proceeds Ag/HA1.6 composite coating on cell proliferation and cell differentiation obvious impact; the Pulse Electrochemical deposition method EAg/HA0.8 and EAg/HA1.6 composite coating found no cytotoxicity. In antimicrobial capacity, the antimicrobial ability of the two methods resulting coating on Escherichia coli and Staphylococcus albus are increased with increasing coating silver content and can reach a rate of more than 95% of the antimicrobial.

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CLC: > Medicine, health > Basic Medical > Medical science in general > Biomedical Engineering > General issues > Biomaterial
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