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Objective clinical epidemiological methods, factors related to research postherpetic neuralgia (postherpetic neuralgia, PHN), to provide a reference for the clinical prevention of PHN. Research subacute postherpetic neuralgia in patients with herpes zoster, clinical characteristics, acute pain of herpes zoster, the relationship between the sub-acute herpetic neuralgia and PHN. Methods The study collected 1-10 months in 2010, 174 cases of herpes zoster patients in our hospital outpatient and inpatient record age, sex, whether accompanied by fever, with or without prodromal pain involved nerve site, lesion type, lesion area, the degree of acute pain, the time of initial treatment, treatment modalities, and merging internal medicine diseases. Follow-up after the rash 30 days and 4 months of pain. Four months after the rash still persistent pain and determination of PHN; rash after 30 days still persistent pain, but in the four months after the rash has no pain were judged as subacute postherpetic neuralgia. Correlation exists univariate analysis of the above factors and PHN. Derived clinical factors associated with PHN occurs, the occurrence of subacute postherpetic neuralgia patients and the occurrence of PHN patients and patients with acute pain occurs only compare analysis occurrence of subacute postherpetic neuralgia patients Clinical features. All data applications SPSS 11.5 statistical software for statistical analysis. PHN-related factors analysis results showed that age, prodromal pain, lesion type, degree of acute pain, the time of initial treatment, diabetes mellitus, PHN group and did not occur PHN group, the difference was statistically significant (P lt; 0.05). Gender, fever, involvement types of nerve lesions area, application of antiviral drugs, glucocorticoids, combined cardiovascular and cerebrovascular diseases, digestive diseases, respiratory diseases, malignant tumors, connective tissue disease of PHN group and did not occur PHN group, the difference was not statistically significance (P gt; 0.05). The occurrence of subacute postherpetic neuralgia occurred PHN, patient age and acute pain severity difference was statistically significant (P lt; 0.05). Subacute herpes zoster neuralgia by the acute pain occurs only difference was statistically significant (P lt; 0.05), lesion type. Conclusion Age, with or without prodromal pain, lesion type, degree of acute pain, the time of initial treatment, the occurrence of diabetes mellitus and of PHN. Gender, fever, affected nerve area the lesions area, antivirals, glucocorticoids, combined heart and cerebrovascular diseases, digestive diseases, respiratory diseases, malignant tumors, connective tissue disease, PHN occurrence unrelated. Old age, prodromal pain, serious type of skin lesions, severe pain in the acute phase, the initial treatment late, diabetes, PHN incidence increased. Tip age, prodromal pain, severe skin lesions, severe acute pain, or diabetes, herpes zoster patients should be concerned, active and effective early treatment to reduce the probability of occurrence of PHN. Occurrence of subacute postherpetic neuralgia young, acute pain to a lesser extent than the occurrence of PHN. Occurrence of subacute herpes zoster neuralgia who only acute pain, lesion type is more serious. Prompted subacute postherpetic neuralgia and not just the time on the transition between acute herpes zoster pain and PHN among possible existence of a more complex relationship.
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