Dissertation > Excellent graduate degree dissertation topics show

The Study of Cognition Function and Impulsive Aggressive Personatlity in Inpatients with Mental Disorder Due to Use of Methamphetamine

Author: WangHui
Tutor: SuZhongHua
School: Shandong University
Course: Internal Medicine
Keywords: Amphetamine-Induced Psychiatric Disorders Cognitive Function Impulsive Aggressive Personality
CLC: R749.1
Type: Master's thesis
Year: 2011
Downloads: 81
Quote: 0
Read: Download Dissertation

Abstract


Objective:To investigate the characteristics of the cognitive impairment, impulsive and aggressive personality in the inpatients with mental disorders due to use of amphetamine,and explore the outcomes after the antipsychotic treatment lasted one month.Methods:Adopt case control study.The patients of the Amphetamine-induced psychiatric disorders group were selected randomly from Shandong Ankang Hospital during the period of the drug addicts undergoing treatment.A total of 100 patients were enrolled in the study.90 cases were male,10 cases were female.The cognition function of all patients were assessed with Attentional Network Test (ANT),Mental Rotation,Iowa Gambling Task,Wisconsin Card Sorting Test,N-back test in the first week (±3 days) and the fourth week (±3 days);The impulsive aggressive personality of all patients were assessed with Barratt Impulsivity Scale and Barratt Aggressive Scale.All data was analyzed by the statistic software of SPSS 12.0, and p<0.05 was considered to be the statistical significance.Result:The Result of Cognition Function:(1)Attentional Network Function: Compared with the control group,the first ANT’s response time was significantly increased,the correct rate,orienting and executive control network of Amphetamine-induced psychiatric disorders were significantly reduced ((eg:response time 867.37±272.24ms/668.56±136.20ms,correct rate 0.88±0.06/0.88±0.06, orienting-217.86±198.00ms/59.67±85.07 ms and executive control network 184.74±66.61ms/74.71±50.77 ms,P<0.05),but the alerting network was higher (eg:151.17±198.27ms/50.60±67.47ms).In the second ANT results,there was no significant difference between two groups.Compared with the first ANT results,the second ANT has higher scores in response time,the correct rate,orienting and executive control network (eg:response time 867.37±272.24ms/650.52±136.69ms,correct rate 0.88±0.06/0.99±0.01,orienting-217.86±198.00 ms/-67.56±77.20 ms,P<0.05) and executive control network,but the alerting network was lower (eg:alerting network 51.17±198.27ms/34.11±74.20ms, P >0.05).(2) Decision Making Function:Compared with the control group,Patients with Amphetamine-induced psychiatric disorders were trent to choose cards from the disadvantageous in the first Iowa Gambling Task test, there was significant difference between two groups (P<0.05).The Amphetamine-induced psychiatric disorders group were trent to choose cards from the disadvantageous in the second Iowa Gambling Task test, there was significant difference between two groups (P<0.05).The second Iowa Gambling Task test were better than the first Iowa Gambling Task test performance,there was significant difference between two groups (P<0.05). (3) Executive Function:Compared with the control group,Patients with Amphetamine-induced psychiatric disorders has poorer results in WCST(P<0.01), In the second WCST results,there was no significant difference between two groups (P>0.05).The second WCST were better than the first WCST performance (P<0.01).(4) Mental Rotation Function:Compared with the control group,Patients with Amphetamine-induced psychiatric disorders has poorer results in Mental Rotation,there was significant difference between two groups (P<0.01), In the second Mental Rotation results,there was no significant difference between two groups (P>0.05).The second Mental Rotation were better than the first Mental Rotation performance,there was significant difference between two groups (P<0.01).The same to control group Amphetamine-induced psychiatric disorders had longest reaction time in rotation angle of 180 degrees but had shortest reaction time in rotation angle of 0 degrees. (5) N-back Test:Compared with the control group,the first N-back Test’s response time was higher,but the correct rate was lower (P<0.01);but the second N-back Test’s has no significant difference between two groups.Compared with the first N-back Test’s results,the second N-back Test’s has shorter time,higher correct rate (P<0.01).The Result of Impulsive Aggressive Personality:Compared with the control group,patients with Amphetamine-induced psychiatric disorders has high scores in the first Barratt Impulsivity Scale and Buss Aggressive Scale (P<0.05).In the second results of Barratt Impulsivity Scale and Buss Aggressive Scale,there was significant difference between two groups (P<0.01).The first has higher scords than the second, there was significant difference between two groups (P<0.01)Conclusion:These results suggest that Amphetamine-induced psychiatric disorders has impairment in cognitive function, these could be recovered within one month by antipsychotic treatment. Amphetamine-induced psychiatric disorders has higher Impulsive Aggressive behavior.

Related Dissertations

  1. Effects of Partial Hepatic Ischemia/Reperfusion Injury on Postoperative Cognitive Function in Mice,R614
  2. Roles of Small Conductance Calcium-activated Potassium Channels in Mice with Alzheimer’s Disease,R749.16
  3. The Study of Cognitive Fuction, Sleep Structure and Diurnal Blood Pressure in Stoke Combined with Obstructive Sleep Apneah Hypopnea Syndrome,R743.3
  4. Research of Impuisivity and Aggressive Personality and Cognitive Function in Inpatients with Internet Addiction,R749.99
  5. A ~1H Magnetic Resonance Spectroscopy Imaging Study and a Cognitive Function Research of Obsessive-compulsive Disorder,R749.7
  6. The Clinical Study of Cognitive Dysfunction after Coronary Artery Bypass Graft,R614
  7. Existential Sentences in the first term and the term structure,H146
  8. Age-related white matter changes and the number of peripheral blood progenitor cells and study the relationship between cognitive function,R743.3
  9. Adult Neurogenesis for Cognitive Function Repair after Graded Traumatic Hippocampus Injury,R651.1
  10. A Cognitive-Functional Analysis of Discourse Coherence,H05
  11. Pumping dirty flat on twitch - Tourette Syndrome Clinical Observation,R749.94
  12. Cognitive dysfunction in diabetic rats and GFAP expression and insulin intervention impact,R749.2
  13. Changsha urban elderly cognitive function and its influencing factors research,R749.1
  14. The Study of Leukoaraiosis by Diffusion Weighted Imaging and Diffusion Tensor Imaging,R742
  15. Effects of HMG-CoA Reductase Inhibitors on Primary Hypertension Patients with Vascular Cognitive Impairment,R544.1
  16. Cognitive Function, Metabolism of Amyloid Precursor Protein and Effect of Pioglitazone Intervention in the Brain of Insulin Resistance Rats,R587.1
  17. Effects of Different Anesthesia on Cognition Function and Serum S100β Protein Levels in Geriatric Patients Following Off-pump Coronary Artery Bypass Grafting,R614
  18. A Study in Cognition of School-age Children with Epilepsy Treated by the Phenobarbital and an Analysis of Related Factors in Those Cognitions,R742.1
  19. Multiple Sclerosis Patients: Neuropsychological and Diffusion-Tensor Imaging Study,R744.51
  20. Analysis of Depression EEG Signals with Neural Oscillation,R749.4
  21. Influence of Resveratrol on the Expression of β-amyloid Protein in Model Mice with Alzheimer’s Disease,R285.5

CLC: > Medicine, health > Neurology and psychiatry > Psychiatry > Cerebral organic mental disorder
© 2012 www.DissertationTopic.Net  Mobile