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Objective: view Chaxin stomach particles precancerous lesions ( PLGC ) ( Qi and Yin stasis toxin ) in patients with epidermal growth factor (EGF) levels in the explore Xin stomach particles PLGC treatment mechanism , further observation drug clinical efficacy and safety . Methods: PLGC patients met the inclusion criteria , 60 patients were randomly divided into two groups, 30 in each group . The treatment group give Hin stomach particles , the control group was given a piece of Weifuchun , treatment lasted 3 months , were observed in the 2 groups of patients before and after treatment , clinical symptoms , endoscopy , pathology , the HP and serum EGF levels to improve the situation Results: The treatment process The treatment group and control group were two cases fall off, and the final completion of the 56 cases . The results showed that , in total effective , the treatment group total effective rate was 92.86% , total effective rate was 60.71% in the control group ; in clinical syndromes improvement , the total effective rate of 96.43% , 78.50% in the control group ( P lt ; 0.05 ) ; improvement in the degree of endoscopy , pathology , treatment group was significantly higher than that in the control group ( P lt ; 0.05 ) ; in Hp clearance rates , no statistical difference between the treatment group and the control group ( P GT ; 0.05 ) ; in serum EGF expression level of regulation , the treatment group and the control group after treatment were significantly lower in the treatment group compared with the control group decreased more significantly , compared groups was statistically significant ( P lt ; 0.05 ) ; treatment process, the two groups were no significant adverse reactions , blood, urine, stool , and liver and kidney function , ECG had no obvious abnormalities are safe . Conclusion: The results of clinical trials show that welcomes the stomach PLGC efficacy the particles treatment Qiyinliangxu of stasis toxin exact , not only reversed to some extent, the atrophy of the gastric mucosa , intestinal metaplasia and dysplasia of the pathological state , and can be effective control of HP infection . In addition , Yan stomach particles can significantly reduce the level of serum EGF expression , give full play to the Chinese medicine in the treatment PLGC advantage , it is widely used in clinical
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