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Objective: through Gegenqinlian different preparation process decoction in vivo , the comparative study of the role of outside anti-infective explore traditional prescription preparation process caused by the content of the active ingredient , pharmacodynamic differences appears , is by the side of the two times development ideas. Methods : First, three different prepared Gegenqinlian decoction : MD, SD, EAI , a total of ten kinds of selection of standard strains of cocci and enteric bacilli , experimental process , traditional Chinese medicine the dope in vitro antibacterial Experiment 2 containing serum bacteriostatic experiment 3 , the experimental results of the in vivo anti-infective : 1 , the inhibitory effect of Chinese medicine dope , MD , SD, EAI three , P <0.01, presence of a very significant difference ; SD inhibitory effect is greater than the MD, P <0.05 , The difference was statistically significant ; the EAI inhibition greater than MD, P <0.01, both extremely significant difference . 2 , the inhibitory effect of serum containing , MD , SD, EAI three comparison , P <0.01, highly significant differences exist . No significant difference between SD and MD inhibitory effect ; the EAI inhibition greater than MD, P <0.05, the difference was statistically significant . Mitigation role of acute mouse ear inflammation , MD, SD, EAI three comparison , P <0.01, highly significant differences exist . The SD role greater than MD, P <0.05, the difference was statistically significant . The role of EAI is greater than the MD, P <0.01, both very significant difference . Conclusion : Chinese medicine dope of ten kinds strains are inhibited most EAI role . 2 , blank control serum without inhibition , inhibition by the drug-containing serum for ten strains EAI is the strongest . 3 , the three preparation process Gegenqinlian the strongest local inflammation to ease the role of EAI .
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