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The Design of Lumbar Anterior Carbon Fiber Reinforced Interbody Fusion Devices and the Related Study

Author: LiGuo
Tutor: LiJiaShun；JiaLianShun；TanJun
School: Second Military Medical University
Course: Surgery
Keywords: Interbody fusion Carbon fiber Biomechanics Histological Lumbar discogenic disorders
CLC: TH789
Type: PhD thesis
Year: 2004
Downloads: 95
Quote: 0
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Abstract


Objective: To intervertebral height restoration, reconstruction physiological lumbar flexion degree, taking into account the reconstruction of post-lumbar immediate need of stability and long-term bone fusion, to improve the effect of anterior interbody fusion in the lumbar spine, developed in line with people anatomical characteristics of lumbar Road carbon fiber reinforced cage, and biomechanics, the study of animal tissues. Method: development suitable for people lumbar anatomical characteristics of carbon fiber reinforced anterior interbody fusion, and biomechanics, histological studies. The study is divided into three parts: (a) anterior carbon fiber reinforced interbody fusion and the development of carbon fiber ligament. People lumbar intervertebral disc anatomical data on the basis of the relevant literature, summarize, and designed lumbar anterior interbody fusion of lumbar intervertebral disc shape and size suitable for people of their materials, design features and performance; (b) of the anterior carbon fiber reinforced biomechanics of interbody fusion research. Lumbar specimens for a healthy adult subjects experiment of two parts: 1, analog the anterior partial lumbar disc implanted carbon fiber interbody fusion joint of different fixed fusion style instantly stability, different implants and joint fixed way biomechanics research. 8 healthy adult lumbar control group were divided into normal lumbar, iliac bone group, separate anterior carbon fiber reinforced interbody fusion implant group, anterior interbody fusion implants joint posterior pedicle screws and after path translaminar facet screw fixation group, anterior carbon fiber artificial ligament fixed and retained anterior longitudinal ligament side implanted interbody fusion group, respectively, strain, displacement, strength, stiffness, ultimate performance test results were statistically processing; lumbar anterior interbody fusion carbon fiber reinforced pullout force experiments. 6 lumbar motion segment were randomly divided into two groups, were implanted in the iliac and anterior interbody fusion of carbon fiber. Test each of the pull-out strength, and analyzed statistically. (C) anterior carbon fiber reinforced interbody fusion cage and carbon fiber artificial ligament histological observation. 12 canine object randomly divided into a control group (3), the experimental group (6) and artificial ligament implant group (3). Were implanted into the side of the front of the first two sets of rows dogs after lumbar discectomy and the iliac and fill iliac special carbon fiber reinforced interbody fusion, parallel side plate fixation. March and June, with imaging and histological observation and evaluation of the anterior carbon fiber strengthening interbody fusion histocompatibility and interbody fusion. Paraspinal muscles of the dogs in the the artificial ligament implant group, embedding carbon fiber artificial ligament, March underwent histological examination observed carbon fiber artificial ligament tissue compatibility. Results: (a) anterior carbon fiber to strengthen the physical and chemical properties of interbody fusion stable shape designed to meet people disc anatomical characteristics. (B) the results of biomechanical testing alone interbody fusion implant group in the center of compression, flexion, Second Military Medical University doctoral dissertation stretch flexor state strain compared with iliac bone graft group, there are significant differences between Iraq lt; 0.01 ); extension and rotation state than those of a normal control group strain prompts used alone anterior interbody fusion surgery in extension and rotation stability. Anterior carbon fiber reinforced interbody fusion cage implantation combined with posterior pedicle screw fixation increased strength and stiffness of the various state and are greater than the experimental group. Posterior translaminar facet joint screws and anterior carbon fiber artificial ligament reconstruction of the anterior longitudinal ligament strain and displacement can reduce the stretching direction, may also increase the stiffness of the rotation between the two was no significant sex difference (P gt; 0.05) . Retain stability in the stretching direction between the separate anterior interbody fusion implants and anterior interbody fusion intraocular carbon fiber ligaments in front of fixed surgical implant anterior interbody fusion anterior longitudinal ligament side, the three more significant differences between the torsional strength is significantly lower than the anterior interbody fusion combined carbon fiber front of the artificial ligament fixation type, there is a statistically significant difference (P lt; 0 .05). Limit mechanical performance tests show that carbon fiber interbody fusion late in the lumbar spine specimens destruction. The withdrawal force experimental results show that lumbar anterior carbon fiber reinforced interbody fusion pullout force of 520 N, significantly higher than the iliac bone implantation group. (C) Histological observation showed that the carbon fiber interbody fusion implant intervertebral March, interbody fusion around the fiber cells and a small amount of cartilage cell growth after implantation June interbody fusion with bone interface a large number of chondrocytes and portion osteoblast cell growth. Paravertebral intramuscular embedding artificial carbon fiber March histological observation, no inflammatory cell infiltration. Conclusion: Anterior carbon fiber to strengthen in line with people interbody fusion lumbar intervertebral disc anatomical characteristics. Individually implanted interbody fusion anterior carbon fiber reinforced to increase the stability of the axial, flexion and lateral bending, fixed to meet the additional needs of mechanical stability. Artificial carbon fiber ligament anterior fixed increase the stability and to the stability of the extending direction of extension and rotation. Histological studies have shown that the carbon fiber reinforced interbody fusion and artificial ligament has good histocompatibility.

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