Dissertation > Excellent graduate degree dissertation topics show

The Preliminary Study of Super Paramagnetic Plasmid Controlledrelease Microspheres for Enhancing of Angiogenesis of Artificial Bone

Author: LuoCong
Tutor: AnHong
School: Chongqing Medical University
Course: Surgery
Keywords: superparamagnetism nano-Fe3O4 gene chitosan gelatin microsphere artificial bone vasculogenesis anagenesis static magnetic field oscillating magneticfield
CLC: R318.17
Type: PhD thesis
Year: 2006
Downloads: 217
Quote: 0
Read: Download Dissertation


Objective: The superparamagnetic chitosan plasmid(pDsVEGF165Red1-N1)gelatin microspheres (SPCPGM) were prepared and filling into the porosity cages of biological activity artificial bone. The ability of the controlled release and local concentration of the plasmid DNA were investigated in vitro under a static magnetic field or an oscillating magnetic field. In vivo, the efficiency of slow release, controlled release, local concentration and delivery of the plasmid DNA for enhancement of angiogenesis and osteogenesis were evaluated under a static magnetic field and / or an oscillating magnetic field to know whether it could enhance local angiogenesis and osteogenesis and discuss value of clinical application in the future.Methods:⑴The superparamagnetic Fe3O4 chitosan nanoparticles (SPFCN) were prepared by a chemical co-precipitation, the appearance and size of the nanoparticales was surveyed with a Transmission Electron Microscope, The grain distributeon, zeta potentials and magnetic properties of the nanoparticles were determined with a Laser Particle Size Analyzer, a Malvern Zetasizer and a Magnetic Balance, respectively.⑵The recombinant eukaryotic expressive plasmids that can expresse the fusion protein of red fluorescent protein and

Related Dissertations

  1. Research and Implementation on Knowledge Representation of Gene Regulatory Network,Q78
  2. Research on Combinatorial Regulation of Multiple Transcription Factors,Q78
  3. Cloning and Expression of CHS and CHI Genes and Their Regulation on the Accumulation of Flavonoids in ’Cara Cara’ Navel Orange (Citrus Sinensis Osbeck) and ’Guoqing NO.4’ Satsuma Mandarin (Citrus Unshiu Marcow),S666.4
  4. Studies on Chitosan and Its Derivatives Adsorption for Paralytic Shellfish Poisoning in Ostrea Rivularis Could,TS254.4
  5. Chemical Structures and Mechanism Research of Anti-aging Leading Compounds from Natural Products,R285.5
  6. CYP2C19 Gene Polymorphism in Patients with Ischemic Cerebrovascular,R743
  7. The Expression Survey of BMP Signalling Pathway in the Human Embryonic Tooth Germ,R78
  8. Cloning and Expression of Growth Hormone Gene in Cobia (Rachycentron Canadus),Q786
  9. Study on Morphologies of Some Urushiol Metal Polymers Films by Breath Figure Method,O634
  10. Thermal Stability of Complexes of Chitosan Quaternary Ammonium Salt and Metal Ion,O634
  11. Effects of Different Reconciled Corn Oils on Antioxidative Stress, Lipid Metabolism Enzymes, and Abundance of Immune-related Genes of Broilers,S831.5
  12. Polyethylenimine Conjugated Stearic Acid-g-chitosan Oligosaccharide Micelles for Antitumor Gene Therapy,R450
  13. Preparation and Characterization of the OCS/PLLA Composite Film for Biomedical Materials,R318.08
  14. An Approach for Identifying a Plant Resistance Gene Based on the Random Forest,Q943
  15. Study on the Accumulation and Remove of Cadmium and Lead in Oysters,X174
  16. Study on the Synthesis and Adsorption Behaviour of Chitosan Derivative,TS254.9
  17. Improvement of Preparation Technology for Chitin and Chitosan from By-product of Litopenaeus Vannamei,TS254.9
  18. Functional Analysis of Proteins Encoded by RNA2 of Wheat Yellow Mosaic Virus,S435.121
  19. Comparative Study on Reproductive Biological Characteristics of Helicoverpa Armigera and Helicoverpa Assulta (Lepidoptera:Nuctuidae),S433
  20. Preliminary Study on the Biological Control Potential of the Hypovirus CHV1-CN280 and Functional Analysis of P29,S436.64
  21. The Detection of the Virulence-related Gene from Vibrio Alginolyticus and the Study on Preservation Methods,S943

CLC: > Medicine, health > Basic Medical > Medical science in general > Biomedical Engineering > Artificial organs and organ > Moving organs
© 2012 www.DissertationTopic.Net  Mobile