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Research and Construction of Ontology-based Clinical Pathway Knowledge Base

Author: FengZhenZhen
Tutor: ZhengXiChuan
School: Suzhou University
Course: Biomedical Engineering
Keywords: ontology clinical pathway knowledge base protégé SWRL
CLC: R197.3
Type: Master's thesis
Year: 2012
Downloads: 111
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In order to improve the medical quality, control hospitalization costs and reducemalpractice, clinical pathway management has been introduced by medical institutionsin many countries. In our country, the ministry of health promulgated one hundredclinical pathways of common disease at the end of2009, and developed a pilot work ona national scale. Clinical pathway becomes the effective means to standard the behaviorof clinical diagnosis and treats, guarantee medical care quality and medical insuranceand reduce randomness for the treatment process.Clinical pathway can decrease medical randomness and reduce medical costs tosome extent through standardizing the treatment process, but there is also a bigdisadvantage to patients whose personalized differences are significant. Even thepatient have the same disease, their particular cases are different. So it is wrong toexecute the treatment completely according to the pathway. However, at present mostelectronic clinical pathway applications are static, they do not support dynamic adaptiveclinical pathway. So, in order to address the problem we proposed to construct evidencebased clinical pathway knowledge base.Considering about the complexity and relativity of clinical information, wepresented to construct ontology-based clinical pathway knowledge base for decisionsupport through knowledge reasoning. We first collected and analyzed five kinds ofclinical pathway data source, and extracted the basic knowledge elements. Thenconstructed the clinical pathway ontology using Protégé and write the related rules offive paths using SWRL language, thus the ontology base and rule base are completed.The ontology can be filled by patient’s clinical data cases using D2R and SPARQL. Weused Jess reasoning engine realizing the clinical pathway knowledge reason on protégéplatform, and we also realized experimental implementation of the system using Jenaframework on the Eclipse platform. In addition we discussed the extended application of clinical pathway knowledge base, including the integration with EMR and therealization of regional clinical pathway knowledge base.

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CLC: > Medicine, health > Preventive Medicine,Health > Health care organizations and career ( Health Management ) > Health care systems and institutions > Hospitals, general hospitals
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