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The Value of Corrected BMD by BMI in Diagnosis of Osteoporsis

Author: JinHaiJian
Tutor: DengZhongLiang
School: Chongqing Medical University
Course: Clinical
Keywords: osteoporotic fracture postmenopausal women body massindex correct bone mineral density
CLC: R58
Type: Master's thesis
Year: 2012
Downloads: 64
Quote: 0
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Abstract


Objective:BMI corrected BMD Contrast with BMD in diagnosis of soteoporsis of47old women who had occurred a fracture and110postmenopausal women,and provide reference for terpretation of BMD in clinical.Method:analyse47old women’s clinical data whose lumbar or neck of femur had occurred a fracture, Observe and analyse the BMD of lumbar or neck,then use BMI to correct BMD and contrast with BMD in diagnosis of soteoporsis and discuss. Then Use XR-46to measure the bone mineral density(BMD) of L2-4、left femoral neck of all the110postmenopausal women, meanwhile record body height, body weight and calculate the body mass index. The subjects were grouped according to bone mineral density, those whose BMD of L2-4or neck declines more than2.5standard deviation compared with the young adult were assigned to the osteoporosis group (OP), others were assigned to the non-osteoporosis group (Non-OP). The OP group have71cases,accounting for64.5%of all the110subjects; Non-OP group have39cases,and take the percentage of35.5%.Then use BMI to correct BMD and contrast with BMD in diagnosis of soteoporsis and discuss.Results:The average age of47old women is(72.289±11.105),from59to91years old.Before the calibration, there are35cases whose BMD T<-2.5and12cases whose BMD T≥-2.5(74.5%and25.5%separately) of total47cases; after the calibration, there are43cases whose BMD T<-2.5and4cases whose BMD T≥-2.5(91.5%and8.5%separately) of total47cases; The relevance ratio of CBMD and BMD have statistical differences(p<0.05).There are no patients△T≥-2.5, for whose BMD T<-2.5before the calibration, and there are8patients△T<-2.5, for whose BMD T≥-2.5before the calibration.The average age of all the110postmenopausal women is (58.582±11.157),from47to88years old.Before the calibration, there are71cases whose BMD T<-2.5and39cases whose BMD T≥-2.5(64.5%and35.5%separately) of total110cases; after the calibration, there are81cases whose BMD T<-2.5and29cases whose BMD T≥-2.5(73.6%and26.4%separately) of total110cases; The relevance ratio of CBMD and BMD have no statistical differences(p>0.05).There are21patients△T≥-2.5, for whose BMD T<-2.5before the calibration, and there are11patients△T<-2.5, for whose BMD T≥-2.5before the calibration.Conclusion:1. Routine examination of BMD for the diagnosis of osteoporosis is not consistent with the risk of fracture.2.BMI can effects on BMD, people who have high BMI can have a higher BMD than those with low BMI.3.Use BMI to correct BMD can improve in predicting the risk of fracture.4.Use△T=T-(BMI-23) x|T|/23to correct BMD may more conform to the actual situation.

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