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Prevalence of Metabolic Syndrome and White Blood Cell Count, Red Blood Cell Distribution Width Associated with Its Components among Steel Industry Employee in Guangzhou City

Author: MoPei
Tutor: LiuShiMing
School: Guangzhou Medical College
Course: Department of Cardiology
Keywords: Metabolic syndrome White blood cell count Red cell distribution width
CLC: R589
Type: Master's thesis
Year: 2011
Downloads: 45
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Abstract


Objective To investigate the prevalence of Guangzhou Iron and Steel practitioners of metabolic syndrome and related disorders (metabolic syndrome, MS) situation, analyze the risk factors associated with metabolic syndrome in the crowd, to further explore the white blood cell count, and the relationship between red blood cell distribution width and the metabolic syndrome. Methods A cluster random sample of 16 units of Guangzhou Iron and Steel Group 4,241 employees (20-60 years old) questionnaire and physical examination. Data were analyzed using MS diagnostic criteria of the International Diabetes Federation (IDF). With SPSS13.0 software for statistical analysis, descriptive analysis of the data on the total population; compared by χ2 test, standardized computing standard on the 2000 national census data. MS-related risk factors with the χ2 test and Logistic regression analysis was calculated OR values ??of the relevant factors. The crowd was divided into 3 groups according to high and low white blood cell count, the application MS analysis of variance analysis and white blood cell count, OR Logistic regression analysis calculated value. Crowd by red blood cell distribution width high and low divided into four groups and describes the general characteristics of the population, analysis of variance analysis of the relationship between red blood cell distribution width, RDW gt; 0.14 defined as RDW elevated OR values ??of the relevant factors calculated by logistic regression analysis. MS results Guangzhou Iron and Steel Group MS Prevalence of of 1.1 metabolic syndrome and its components prevalence crude prevalence rate was 9.70% (male 9.80%, female 9.40%) after age and sex standardized prevalence 7.95% (male 8.87%, female 6.97%); central obesity, high TG hypertriglyceridemia, low HDL-CH hyperlipidemia, high blood pressure, high FPG / diabetes standards prevalence of 15.84%, 27.04%, 20.46%, 17.19%, 8.29%; prevalence of metabolic syndrome differences between men and women was not statistically significant, the men's high TG hyperlipidemia, high blood pressure, high FPG / diabetes prevalence in women (P lt; 0.05), while women with central obesity, hyperlipidemia prevalence of low HDL-C than men (P lt; 0.05). Metabolic syndrome, central obesity, the high TG hyperlipidemia, high blood pressure, the the high FPG / prevalence of diabetes has increased with increasing age trend, and the difference was statistically significant (P lt; 0.05). By BMI into normal, overweight and obesity groups, the prevalence rate of metabolic syndrome and its individual components of metabolic abnormalities was significantly increased with BMI, the difference was statistically significant (P lt; 0.05). 1.2 components of the distribution of elevated blood pressure in metabolic syndrome (92.7%) in the highest frequency in patients with metabolic syndrome, followed by the the high TG hyperlipidemia (85.2%), low HDL-CH hyperlipidemia (34.3%), high FPG / diabetes (20.5%) the lowest. Distribution of the survey population of 1.3 MS related metabolic abnormalities components metabolic abnormalities, only 44.3% of women with an abnormal metabolism and central obesity merge one or the prevalence of these metabolic abnormalities in males (P lt; 0.05). 2 Guangzhou Iron and Steel Group MS risk factors the age (OR1.717), BMI (OR 2.110), the high waist-to-hip ratio (OR1.853), drinking (OR1.361), lack movement (OR4.085), family history of hypertension (OR1.342), hyperuricemia (OR1.717), smoking index (OR4.454) is an independent risk factor for the metabolic syndrome. Relationship of the white blood cell count with MS 3.1 general characteristics of male practitioners Guangzhou Iron and Steel population in the white blood cell count stratification in age, body weight, systolic blood pressure, diastolic blood pressure, abdominal circumference, BMI, TC, TG, LDL-CH, UA level and lack of physical activity, history of hypertension, history of diabetes ratio with elevated white blood cell count and increased HDL-CH and high temperature ratio decreases with leukocytosis, the difference was statistically significant (P lt; 0.05). Women, weight, abdominal circumference, BMI, of TG, UA with elevated white blood cell count and increased HDL-CH reduced leukocytosis, the difference was statistically significant (P lt; 0.05). FPG and white blood cell count in men and women, there was no significant relationship. 3.2 metabolic syndrome and related metabolic disorders component and white blood cell count male relationship in addition to high blood sugar, white blood cell count of the population of the metabolic syndrome and related metabolic abnormalities component than those without the metabolic syndrome and related metabolic abnormalities components of the crowd increased, the difference was statistically significant (P lt; 0.05). OR value of the MS population with elevated white blood cell count increased, the difference was statistically significant (P lt; 0.05). In women, showed no such relationship. 3.3 different metabolic syndrome metabolic abnormalities group number of the white blood cell count related metabolic abnormalities components increases with the metabolic syndrome and elevated white blood cell count in men and women, the difference was statistically significant (P lt; 0.05). Relationship between red blood cell distribution width with MS 4.1 Guangzhou Iron and Steel practitioners crowd in red blood cell distribution width stratification in the general characteristics of men in the age, TC, TG, LDL-CH, HB, MCV and high temperature work, alcohol consumption, history of hypertension, diabetes increased the ratio of a history with the RDW elevated HDL-CH, TP, HB, MCV elevated RDW lower, the difference was statistically significant (P lt; 0.05); women have a history of high blood pressure The ratio increased with the increase of RDW's and TC, HB, MCV With RDW elevated lower, the difference was statistically significant (P lt; 0.05). Of 4.2 metabolic syndrome and related metabolic abnormalities components red cell distribution width relationship in addition to the female hyperglycemia, metabolic syndrome and other metabolic abnormalities component crowd of RDW more components of metabolic syndrome and other metabolic abnormalities crowd increased, the difference was statistically significant (P lt; 0.05). The OR have metabolic syndrome and related metabolic disorders crowd significantly higher in the case of elevated RDW (gt; 14%). 4.3 metabolic syndrome metabolic abnormal group the number of red blood cell distribution width relationship in men, women RDW increase with the metabolic syndrome related metabolic abnormalities components increased, the difference was statistically significant (P lt; 0.05). Conclusion 1 20 to 60-year-old Guangzhou Guangzhou Iron and Steel practitioners crowd of MS prevalence was 7.95%; prevalence of MS metabolic abnormalities components and individuals gathered in this population has been more common; age, BMI, high waist-to-hip ratio, alcohol consumption , exercise, family history of hypertension, hyperuricemia, smoking index is an independent risk factor for MS. White blood cell count, and young and middle-aged men metabolic syndrome and related metabolic components are closely related. This paper shows that the rise in the Chinese the Zhongqing population in RDW with metabolic syndrome is closely related to.

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CLC: > Medicine, health > Internal Medicine > Endocrine diseases and metabolic diseases > Metabolic diseases
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