Dissertation > Excellent graduate degree dissertation topics show

Process Development for Hydrolysis of Methyl Glycolate to Glycolic Acid

Author: ZhangChao
Tutor: LeQingHua
School: East China University of Science and Technology
Course: Chemical Engineering
Keywords: glycolic acid methyl glycolate batch catalytic distillation reaction kinetics
CLC: TQ225
Type: Master's thesis
Year: 2014
Downloads: 22
Quote: 0
Read: Download Dissertation

Abstract


A new hydrolysis process of methyl glycolate(MG) to glycolic acid(GA) was studied in this thesis in order to tackle the prevalent problems in the traditional glycolic acid industry production process, such as pollution, serious corrosion and complicated final treatment. And the feasibility of introducing the catalytic distillation technology in the process was also studied.Under the condition of no catalysts, the effects of initial water-MG molar ratio and reaction temperature on the hydrolysis of methyl glycolate were investigated to find out the boundary conditions. Six different resins were compared in terms of the catalytic activity, and the result showed that001×7ion exchange resin was an effective catalyst for this reaction. And then the kinetics of hydrolysis of MG over001×7ion exchange resin was studied. Then the feasibility of using the catalytic distillation technology in the hydrolysis of MG was studied, and the effects of the initial water-MG molar ratio, the tower heating power, the reflux ratio and the operating pressure were investigated.Experimental results showed that without catalysts the final conversion of MG increased when the initial mole ratio increased; and when the temperature increased, the hydrolysis rate increased significantly, but the final conversion of MG had no obvious change. In order to avoid the by-product, the value of initial molar ratio should be greater than4:1and the temperature should be less than100℃. The kinetics of the hydrolysis of MG over001×7resin was evaluated by the use of the pseudohomogeneous model as follow:The experimental data were correlated by the model, the kinetics parameters were as follows:k0=70.901mol/(g min), E=27.614kJ/mol, c=0.41, d=0.12,e=0.10,f=2.93。Conclusions can be drawn from the research of the batch reactive distillation that the final conversion of MG could be promoted significantly by using this technology. When the value of initial molar ratio was greater than10:1, the operating pressure was about50KPa, the tower heating power was around30W and the reflux ratio is less than2, the conversion of MG could be almost100%in240minutes. The throughput capacity increased when the initial molar ratio or the tower heating power increased.

Related Dissertations

  1. Bevacizumab -PLGA Microspheres intravitreal injection in rabbit eyes pharmacokinetics and distribution of drugs,R96
  2. Intravitreal injection of bevacizumab PLGA Microspheres Synthesis and identification of,R943
  3. The Synthesis and Purification of Methyl Glycolate,TQ225.24
  4. Study on Catalyst and Process of Catalytic Hydrogenation for Dimethyl Oxalate to Methyl Glycollate,TQ225.24
  5. Process Development for Hydrogenation of Dimethyl Oxalate to Methyl Glycolate,TQ225.24
  6. Studies on the Preparation and Properties of ACF/PLGA Scaffolds for Bone Tissue Engineering,R318.08
  7. Electrochemical Treatment of pesticide intermediates ( phthalonitrile ) Wastewater,X786
  8. Experimental Research on the Characteristics of Brown Coal Pyrolysis and Gasification,TQ541
  9. ZnO catalyzed alcoholysis of urea manufacturing process and kinetics of methyl carbamate,TQ225.241
  10. Study on the Kinetic of Non-catalytic Esterification to Produce Benzyl Benzoate and the Application in Benzoic Acid Purification,TQ245.1
  11. Preparation, Identification and Biological Evaluation of Oxidation Products of (-)-Epigallocatechin-3-O-gallate,TQ463
  12. Study on the New Technology of Synthesis of Isooctyl Mercaptoacetate,TQ225.241
  13. Study on Synthesis and Reaction Kinetics of Diphenyl Phosphorazidate by Phase Transfer Catalysis,TQ203.2
  14. Study on the Coupling Technics of Reaction-Adsorption for Dimethyl Adipate,TQ225.24
  15. Studies on Resorcinol Selective Hydrogenation to Prepare 1,3-cyclohexanedione,TQ234.21
  16. Studies on Braintide-PLGA Microspheres,R94
  17. An Experimental Study on Compatibility of Bone Marrow Mesenchymal Stem Cells and Polylactic Glycolic Acid Scaffold, and the Effects of Both Composite Which Restore to Peripheral Nerve Injury,R651.3
  18. An Experimental Study of FK506 Slow-Releasing Polyglycolic Acid Conduits for Tibal Nerve Reconstruction in Rats,R651.3
  19. Reactivity of Yima Coal Gasification,TQ541
  20. Study on Using Microfilaments Diameter of Repairing Peripheral Nerve Defect Using PLGA Three-dimensional Conduit,R651.3
  21. Optimization and Simulation of Reaction Process for Cyclohexanecarboxylic Acid Nitrosation,TQ236

CLC: > Industrial Technology > Chemical Industry > Basic Organic Chemistry Industry > The production of aliphatic compounds ( acyclic compounds) > Aliphatic carboxylic acid and its derivatives
© 2012 www.DissertationTopic.Net  Mobile