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Clinical evaluation of Xinkai kujiangfang intervention on the psychological state of patients with reflux esophagitis of spirit

Author: ChenJian
Tutor: WeiZuo
School: Beijing University of Traditional Chinese Medicine
Course: Traditional Chinese Medicine
Keywords: reflux esophagitis cold and hot symptom psychologicalfactors xinkaikujiang clinical observation
CLC: R259
Type: Master's thesis
Year: 2014
Downloads: 1
Quote: 0
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Abstract


Objectives To evaluate the psychological state of reflux esophagitis (RE) patients by Hamilton depression scale (HAMD) and Hamilton anxiety scale (HAMA); to explore the intervention effect of the treatment of Xinkaikujiang fang on the psychological state of reflux esophagitis patients who are differentiated into cold and hot symptom.Methonds Randomly selected66patients who meet the diagnostic criteria for RE, then divided them into treatment group and control group,each group had33cases.Treatment group received rabeprazole sodium enteric-coated capsules20mg qd and oral administration of Chinese medicine decoction of xinkaikujiang formula granule150ml bid;the control group were treated using rabeprazole sodium enteric-coated capsules20mg qd and chaomaiya formula granule150ml bid.The process was4weeks.All the patients were received survey researeh,which including clinical symptoms,psychological state before and after the treatment. Applying for SPSS17.0software, this study statistically evaluate its efficacy.Results1In66cases of RE patients,the age of the youngest is24years old, the oldest65years old, the average age was48.35±12.41years old, the peak incidence in the age of54-65years old.2There were34cases of depression, anxiety in patients with35cases,and both anxiety and depression in patients with28cases.3The depression and anxiety scores of reflux esophagitis in patients were positively correlated with clinical symptom score,R values were0.496and0.427.4For patients with RE, two groups of drugs have improved their psychological state, and the efficacy of treatment group was superior to the control group, showing the intervention effect of Xinkaikujiang fang on RE patients psychological state. Xinkaikujiang fang can effectively improve the psychological status of patients.5For two groups of RE patients who exist anxiety and depression,the depression and anxiety scores were lower After drug treatment,show that the two groups of drugs on patients with abnormal psychological mental state improved. The patients in treatment group were lower than the control group obviously on mental score, shows Xinkaikujiang fang can effectively improve the psychological status of psychological abnormalities in RE patients.Conclusions1Reflux esophagitis patients have different degree of psychological abnormality.2For RE patients,the depression score,the anxiety score and clinical symptom score was positively related to each other,which are mutual influence,interaction.3Xinkai kujiang fang can interpose the psychological state of RE patients and effectively improve the psychological status.4Xinkaikujiang fang can interpose the psychological state of psychological abnormalities in patients with RE, effectively improve the psychological status.

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