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Objective: To analyze the clinical features and prognosis of acute pancreatitis hyperlipidemic (HLAP). Methods: A retrospective analysis of hyperlipidemic acute pancreatitis patients with 57 cases from January 2000 to December 2009 in the Fujian Medical University, Provincial Clinical Medical College of continuous hospitalization diagnosis. And randomly selected 68 cases for the same period in the diagnosis of patients with acute biliary pancreatitis (ABP) as a control group. Detailed records of the clinical data of the two groups of patients, including age, gender, treatment time, duration of hospitalization, family history, medical history, laboratory parameters, imaging findings, after treatment, concomitant diseases, local and systemic complications, prognosis, and The line Ranson score (admission within 48h), APACHE-II score (admission within 48h) and pancreatic Balthazar CT score and both data comparison and correlation analysis of serum triglyceride levels with disease severity HLAP. Results of: HLAP patients age, serum amylase (admission) were lower than the ABP group patients (age: 40.8 ± l1.3 vs 59.4 ± 17.5 years old; to amylase: median 254.0 vs 1083.5U, P lt; 0.05 ). The HLAP group serum triglyceride (TG), low-density lipoprotein cholesterol (LDL-C) levels were significantly higher than the ABP group (TG: 13.7 ± 8.6 vs 1.2 ± 0.9 mmol / L; LDL-C: 3.1 ± 2.5 vs 2.3 ± 0.9mmol / L, P lt; 0.05); serum TG levels, with Ronson rated value, APACHE-Ⅱ score, pancreas Balthazar CT score were not related to sex (P gt; 0.05). The HLAP of serum direct bilirubin (DBIL), alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma-glutamyl transferase (GGT), alkaline phosphatase (ALP) levels were significantly lower than the ABP group (P lt; 0.05). HLAP group associated with the occurrence of fatty liver and diabetes were significantly higher than the ABP group (fatty liver: 63.2% vs 32.4%; diabetes: 36.8% vs. 14.7%, P lt; 0.05); However, two groups associated with differences in hypertension was not statistically significant (P gt; 0.05). Ranson score of two groups of patients, APACHE-Ⅱ score, pancreas Balthazar CT score differences were not statistically significant (P gt; 0.05). HLAP group suffering from severe pancreatitis incidence than the ABP group (38.6% vs 26.4%, P lt; 0.05). HLAP group of patients with acute respiratory distress syndrome (ARDS), renal insufficiency, pancreatic pseudocyst, and a lower incidence of multiple organ failure ABP group, the difference was statistically significant (P lt; 0.05). The relapse rate of HLAP group was significantly higher than the ABP group (47.4% vs 23.5%, P lt; 0.05); while both the surgery and mortality difference was not statistically significant (P gt; 0.05). Conclusion: The the hyperlipidemia acute pancreatitis (HLAP) predilection in young and middle-aged population, the majority of patients admitted to hospital blood amylase was not significant. HLAP easily associated with fatty liver, diabetes, patients with more ABP is even more serious, complicated by ARDS, renal insufficiency, pancreatic pseudocyst, and multi-organ failure, and also is a recurring.
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