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Amino acids are a large number of in-vivo presence of a class of biological ligands, and is the basic structural units of the protein, and enzymes. Various amino acids and metal complexes involved in various metabolic and physiological and biochemical processes of the human body, plays a very important role in the life course. Therefore, the study of metal complexes of amino acids can provide important information and useful basis for in-depth study of the complex organism. In this thesis, the reaction mechanism of L-glutamic acid, L-cysteine, L-phenylalanine and its zinc complex structure and ligand. Determination of electrical conductivity of these three amino acids and their zinc complexes explore the reaction time, reaction temperature, pH of the medium zinc amino acid ligand reaction system to determine the ratio of the zinc complex of three amino acids: L- Glu: Zn of 1:1; L-Cys: Zn 2:1; L-Phe: Zn of 2:1. And on this basis to study the glutamate zinc, the cysteine ??zinc, the phenylalanine zinc complexes Raman and IR spectra analysis of the interaction of amino acids with Zn 2 , and to explore pH, anions zinc amino acid complexes, summed up the law and the reaction mechanism of the three amino acid zinc coordination complexes. In addition, their copper (II), iron (II), iron (III) complexes. The results show that: (1) When the amino acid molecule is in a state of the isoelectric point, amino acid and the oxygen atom of-COO participation and Zn 2 ligand, wherein the carboxyl group of an oxygen atom in the molecule of L-glutamic acid bridge ligand participation and Zn 2 ligand carboxyl oxygen atoms in the L-cysteine, L-phenylalanine molecules by bidentate participation and Zn 2 ligand. (2) When the amino acid at different pH conditions, different ion state exists. When an amino acid to the R-CH 2 -CH (NH 3 ) the state of existence of a-COOH,-NH of the amino acid molecules 3 / sub> . -COOH groups shall contain lone pair of electrons, and Zn can not 2 coordination. When amino acids R-CH 2 -CH (NH 2 ), the-COO - state present in the amino acid molecules-NH in 2 -COO - in both groups to Zn 2 lone pair of electrons involved in pairing-COO-oxygen atoms of monodentate ligand ligand. (3) preparation of zinc amino acid complexes, the coordination reaction system in the presence of coexisting ions (SO 4 2 - , NO 3 - ), SO 4 2 - , NO 3 - to a single teeth bidentate way involved in the formation of complexes, to change the composition and structure of the complexes. (4) amino acids to the amino nitrogen atom, the carboxyl oxygen oxygen atoms with the copper (II), iron (II), iron (III) ligand, while the sulfur atom of the thiol group only with iron (II), iron (III) conducted with bit. Copper (II) to take sp 3 hybrid coordination to the four-coordinate form amino acids, to form a square planar configuration of the amino acid copper (II) complexes; iron (Ⅱ), iron ( III) were taken d 2 sp 3 hybrid form of hexacoordinated coordination, amino acid iron complexes form octahedral configuration. (5) The amino acid copper (II) amino acid stability of iron (II) complexes with the metal is proportional to the ion charge, and the ion radius is inversely proportional. Therefore, both the stability of the complexes: amino acid copper (II) complexes> amino acid iron (II) complexes.
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