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The Clinical Study of Shiweiwendantang to Coronary Heart Disease Angiana Pestoris on Qi Deficiency and Stasis-phlegm Type

Author: YaoXinYan
Tutor: TanYuanSheng
School: Hunan University of Traditional Chinese Medicine
Course: Integrative Medicine Internal Medicine
Keywords: shiweiwendantang coronary heart disease angina pectoris blood-fat CRP qi deficiency and stasis-phlegm type clinical study
CLC: R259
Type: Master's thesis
Year: 2007
Downloads: 5
Quote: 0
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Objective: To observe the clinical effect of shiweiwendantang to coronary heart disease angiana pestoris on qi deficiency and stasis-phlegm type.Methods: Devided 60 cases of stable angina pectoris, which belonged to the type of qi deficiency and stasis-phlegm into the treatment group and the contrast group randomly,each group has 30 examples.The treatment group takes shiweiwendantang, 1 medicinal preparation every day, two times one day; The control group takes TongXinLuo capsule, 4 grains one time, three times one day. Observed the symptoms integral, the ECG change, the clinical efficacy, the chang of blood-fat and CRP of the two groups after and before treatment. Every 4 weeks is one course of treatment, totally observed one course.Results: (1) the total effective rate in the treatment is superior to the contrast group.The significant difference of statistical comparision is obvious (p<0.05). (2) The curative effect of the treatment group on angina pectoris and ECG is superior to the contrast group (p<0.05 ) .(3) The rate of TCM symptom improvement in the treatment is superior to the contrast group .There is significant statistical difference in the comparision of the two groups , suggesting that shiweiwendantang show better efficacy in improving TCM symptom than TongXinLuo capsule. (4) Nitroglycerin stopped or decreased percentage of thetreatment group is significantly superior to the control group(p<0.05) .(5)shiweiwendantang can regulate lipin metabolism ,lower the levelsof blood-fat, which has significant difference in compared with the contrast group(p<0.01) .Conclusions: the shiweiwendaritang is effective in treating coronary heart disease angiana pestoris on qi deficiency andstasis-phlegm type.The mechanisation maybe through improving lipin metabolism and suppressing inflammation mark CRP excessively expression.

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