|
OBJECTIVE: To compare Ⅱ - Ⅲ level macular cystoid edema (CME) in patients with simple intravitreal injection of triamcinolone acetonide (IVTA) and the IVTA United macular grille-like clinical efficacy of laser photocoagulation (MLG), explore cystoid macular edema Clinical treatment. Methods: A case from 2009.3-2010.3 the I hospital eye clinic Ⅱ - Ⅲ level macular cystoid edema (CME) and 37 patients (37), the treatment by the patient voluntary non-randomly selected and divided into two groups of 29 people (29) . Medication groups: simple intravitreal injection of triamcinolone acetonide (IVTA), 14 (14); combination group: IVTA line in January after macular grid pattern laser photocoagulation (MLG), 15 (15). Compared between the two groups in the IVTA treatment before and after treatment in January, March, June, foveal retinal thickness (CMT), best corrected visual acuity (BCVA), and observed after injection intraocular pressure, complications, and macular cystoid edema recurrence. Before treatment, all patients underwent best corrected visual acuity, intraocular pressure, slit lamp microscopy, optical coherence tomography the Scan (OCT), fundus fluorescein angiography (FFA) check. Results: 1 IVTA before treatment and after one month, three months, six months foveal retinal thickness combined group (692.07 ± 142.68), (300.13 ± 159.30), (265.73 ± 143.26) and (212.87 ± 77.76) um; drug group (818.50 ± 142.14), (403.07 ± 163.47), (329.00 ± 149.72) and (484.36 ± 327.03) um. Both of IVTA after 6 months, the combined group and the treatment group difference was statistically significant (F = 11.267, P = 0.002), IVTA before treatment, 1 month after treatment, three months two groups compare There was no statistical difference in significance (P gt; 0.05). 2 IVTA before treatment and after one month, three months, six months BCVA of log-transformed values ??combined group (3.69 ± 0.70), (4.12 ± 0.57), (4.17 ± 0.53) and (4.22 ± 0.58) ; treatment group (3.78 ± 0.56), (4.23 ± 0.39), (4.29 ± 0.31) and (3.66 ± 0.79). Both of IVTA after 6 months, the combined group and the treatment group difference was statistically significant (Z = -2.100, P = 0.037). 3 in the follow-up period of the study, the treatment group CME recurrence eight eyes, jointly recurrence 4 'eye was statistically significant (P lt; 0.05) occurred in 4 patients, all patients with increased intraocular pressure, two cases reducing ocular topical pressure medicine, two cases plus oral medication control. Conclusion: IVTA combined the MLG treatment of Ⅱ - Ⅲ grade cystoid macular edema (CME), can significantly improve vision, reduce macular edema and reduce recurrence. But the small sample size, short duration, and also need to increase the sample further observation.
|